SCHEMBL22606361

SCHEMBL22606361

CC(=O)NCC(=O)N[C@H]1CCNC(=O)CCC(=O)NC[C@@H](C(=O)NCC(N)=O)NC(=O)CNC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.39

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 3/20 0.39
▸ MC1R Q01726 3/20 0.39
▸ TSLP Q969D9 2/20 0.38
▸ TACR2 P21452 1/20 0.36
▸ OPRM1 P35372 1/20 0.35
▸ OPRD1 P41143 1/20 0.35
▸ OPRK1 P41145 1/20 0.35
▸ CTSG P08311 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20362936 0.96 TSLP (0.39) MC4RMC1RTSLPOPRM1OPRD1
SCHEMBL22606167 0.96 TSLP (0.39) TSLPTACR2CTSG
SCHEMBL20206327 0.95 MC4R (0.39) MC4RMC1RTSLPTACR2OPRM1
SCHEMBL20362939 0.95 TSLP (0.39) MC4RMC1RTSLPTACR2OPRM1
SCHEMBL20206173 0.94 TSLP (0.39) MC4RMC1RTSLPOPRM1OPRD1
SCHEMBL20363003 0.91 MC4R (0.40) MC4RMC1RTSLP
SCHEMBL20206167 0.91 FCGRT (0.39) MC4RMC1RTSLP
SCHEMBL22606172 0.91 TSLP (0.38) TSLPTACR2OPRM1OPRD1OPRK1
SCHEMBL20206196 0.89 TUBB4A (0.38) MC4RMC1RTSLPOPRM1OPRD1
SCHEMBL22606199 0.88 MEN1 (0.38) MC4RMC1RTACR2OPRM1OPRD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy PALATIN TECHNOLOGIES, INC. (US) 2022-03-29 — — US disclosed
US-20200339631-A1 Melanocortin-1 Receptor-Specific Peptides for Cytokine Storm and Inflammation Therapy PALATIN TECHNOLOGIES INC (US) 2020-10-29 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy MC3R, MC1R, MC2R MC4R 6/4885MC1R 2/4885TSLP 15/4885
US-20200339631-A1 Melanocortin-1 Receptor-Specific Peptides for Cytokine Storm and Inflammation Therapy MC3R, MC1R, MC2R MC4R 6/4885MC1R 2/4885TSLP 15/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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