SCHEMBL20363003

SCHEMBL20363003

CC(=O)NCC(=O)N[C@H]1CCC(=O)NCCC[C@@H](C(=O)NCC(N)=O)NC(=O)CNC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC1=O

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ MC4R P32245 1/20 0.40
▸ TSLP Q969D9 1/20 0.38
▸ TUBB4A P04350 2/20 0.38
▸ TUBB P07437 2/20 0.38
▸ TUBA3C P0DPH7 2/20 0.38
▸ TUBA1B P68363 2/20 0.38
▸ TUBA4A P68366 2/20 0.38
▸ TUBB4B P68371 2/20 0.38
▸ TUBB3 Q13509 2/20 0.38
▸ TUBB2A Q13885 2/20 0.38
▸ TUBB8 Q3ZCM7 2/20 0.38
▸ TUBA3E Q6PEY2 2/20 0.38
▸ TUBA1A Q71U36 2/20 0.38
▸ TUBA1C Q9BQE3 2/20 0.38
▸ TUBB6 Q9BUF5 2/20 0.38
▸ TUBB2B Q9BVA1 2/20 0.38
▸ TUBB1 Q9H4B7 2/20 0.38
▸ FCGRT P55899 1/20 0.38
▸ MC1R Q01726 3/20 0.37
▸ SIRT2 Q8IXJ6 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20206167 0.98 FCGRT (0.39) MC4RTSLPTUBB4ATUBBTUBA3C
SCHEMBL20206173 0.96 TSLP (0.39) MC4RTSLPTUBB4ATUBBTUBA3C
SCHEMBL20362936 0.94 TSLP (0.39) MC4RTSLPTUBB4ATUBBTUBA3C
SCHEMBL22606167 0.93 TSLP (0.39) TSLPTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL20206327 0.91 MC4R (0.39) MC4RTSLPMC1R
SCHEMBL22606361 0.91 MC4R (0.39) MC4RTSLPMC1R
SCHEMBL20206196 0.91 TUBB4A (0.38) MC4RTSLPTUBB4ATUBBTUBA3C
SCHEMBL20362935 0.90 TSLP (0.37) TSLPTUBB4ATUBBTUBA3CTUBA1B
SCHEMBL20206231 0.89 KEAP1 (0.34) TSLPSIRT2SIRT1SIRT3
SCHEMBL24990007 0.89 MC4R (0.37) MC4RTSLPFCGRTMMP1MMP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy PALATIN TECHNOLOGIES, INC. (US) 2022-03-29 — — US disclosed
US-20200339631-A1 Melanocortin-1 Receptor-Specific Peptides for Cytokine Storm and Inflammation Therapy PALATIN TECHNOLOGIES INC (US) 2020-10-29 — — US disclosed
US-10017539-B2 Melanocortin-1 receptor-specific cyclic hexapeptides PALATIN TECHNOLOGIES, INC. (US) 2018-07-10 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11286280-B2 Melanocortin-1 receptor-specific peptides for cytokine storm and inflammation therapy MC3R, MC1R, MC2R MC4R 6/4885TSLP 15/4885TUBB4A 4234/4885
US-10017539-B2 Melanocortin-1 receptor-specific cyclic hexapeptides MC1R, MC3R, MC5R MC4R 4/4885TSLP 357/4885TUBB4A 4844/4885
US-20200339631-A1 Melanocortin-1 Receptor-Specific Peptides for Cytokine Storm and Inflammation Therapy MC3R, MC1R, MC2R MC4R 6/4885TSLP 15/4885TUBB4A 4234/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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