SCHEMBL508833

SCHEMBL508833

C=C1CCN(C(C)(C)C)C1=O

nearest known ligand 0.33

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CNR1 P21554 1/20 0.33
CNR2 P34972 1/20 0.33
LMNA P02545 1/20 0.31
MAPT P10636 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16492024 0.84 MITF (0.30)
SCHEMBL13698409 0.75 POLB (0.35) LMNAMAPT
SCHEMBL15688368 0.74 LMNA (0.31) LMNAMAPT
SCHEMBL23084196 0.74
SCHEMBL610179 0.70
SCHEMBL14682741 0.70
SCHEMBL17930247 0.70
SCHEMBL232823 0.69
SCHEMBL20206746 0.68 CRBN (0.33)
SCHEMBL509506 0.68 GRM5 (0.34) CNR1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 687 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12638614-B2 Method for making silicone hydrogel contact lenses ALCON INC. (CH) 2026-05-26 US claimed
WO-2026099827-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES ALCON INC. (CH) 2026-05-15 WO claimed
US-20260132236-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES ALCON INC (CH) 2026-05-14 US claimed
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-05-14 US claimed
US-12595368-B2 UV/HEVL-filtering contact lenses ALCON INC. (CH) 2026-04-07 US claimed
EP-4713721-A1 UV/HEVL-FILTERING SILICONE HYDROGEL CONTACT LENSES Alcon Inc. (CH) 2026-03-25 EP claimed
US-12570784-B2 Method for making embedded hydrogel contact lenses ALCON INC. (CH) 2026-03-10 US claimed
EP-3759528-B1 SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
EP-4514596-B1 METHOD FOR MAKING SILICONE HYDROGEL CONTACT LENSES ALCON INC (CH) 2026-03-04 EP claimed
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES ALCON INC (CH) 2026-02-12 US claimed
US-20120029111-A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF ALCON INC. (CH) 2012-02-02 US claimed
WO-2012016097-A2 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF NOVARTIS AG (CH) 2012-02-02 WO claimed
WO-2012016098-A1 A SILICONE HYDROGEL LENS WITH A CROSSLINKED HYDROPHILIC COATING NOVARTIS AG (CH) 2012-02-02 WO claimed
WO-2011075377-A1 METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS NOVARTIS AG (CH) 2011-06-23 WO claimed
WO-2011071790-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES NOVARTIS AG (CH) 2011-06-16 WO claimed
US-20110140292-A1 METHODS FOR MAKING SILICONE HYDROGEL LENSES FROM WATER-BASED LENS FORMULATIONS ALCON INC. (CH) 2011-06-16 US claimed
US-20110133350-A1 METHODS FOR INCREASING THE ION PERMEABILITY OF CONTACT LENSES ALCON INC. (CH) 2011-06-09 US claimed
WO-2011056761-A1 A SILICONE HYDROGEL LENS WITH A GRAFTED HYDROPHILIC COATING NOVARTIS AG (CH) 2011-05-12 WO claimed
US-20110102736-A1 SILICONE HYDROGEL LENS WITH A GRAFTED HYDROPHILIC COATING ALCON INC. (CH) 2011-05-05 US claimed
US-20100298446-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ALCON INC. (CH) 2010-11-25 US claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260132236-A1 LIGHT ABSORBERS FOR OPHTHALMC LENS MATERALS AND DEVICES RAD51, ERCC1, LANCL2 CNR1 607/4885CNR2 373/4885LMNA 543/4885
US-20100298446-A1 ACTINICALLY-CROSSLINKABLE SILOXANE-CONTAINING COPOLYMERS ATRIP, ATR, MACF1 CNR1 4792/4885CNR2 4797/4885LMNA 2157/4885
US-12595368-B2 UV/HEVL-filtering contact lenses UACA, HSPA4L, RAD54L CNR1 4350/4885CNR2 4144/4885LMNA 2948/4885
US-12570784-B2 Method for making embedded hydrogel contact lenses CRYAB, CRYZ, CRYAA CNR1 3711/4885CNR2 3648/4885LMNA 219/4885
US-20120029111-A1 AMPHIPHILIC POLYSILOXANE PREPOLYMERS AND USES THEREOF PIGS, ELOVL1, HACD2 CNR1 793/4885CNR2 1376/4885LMNA 233/4885
US-20260042268-A1 SILICONE HYDROGEL LENSES WITH WATER-RICH SURFACES STRA6, CRYZ, SMCHD1 CNR1 4693/4885CNR2 4648/4885LMNA 182/4885
US-12638614-B2 Method for making silicone hydrogel contact lenses SMCHD1, CRYAA, CRYZ CNR1 4076/4885CNR2 3788/4885LMNA 1330/4885
US-20260131506-A1 METHOD FOR MAKING EMBEDDED HYDROGEL CONTACT LENSES CRYZ, CRYAB, CRYAA CNR1 4111/4885CNR2 3119/4885LMNA 1320/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.