Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2A | P28223 | 8/20 | 0.41 |
| ▸ | HTR2C | P28335 | 8/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 7/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 7/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 6/20 | 0.39 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207515 | 0.90 | SLC6A2 (0.41) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL18404537 | 0.79 | HTR2A (0.47) | HTR2AHTR2COPRL1 | |
| SCHEMBL18176645 | 0.79 | F2RL1 (0.38) | — | |
| SCHEMBL26540975 | 0.77 | PARK7 (0.36) | HTR2AHTR2CSLC6A2SLC6A4 | |
| SCHEMBL16935946 | 0.77 | SLC6A2 (0.62) | SLC6A2SLC6A4SLC6A3 | |
| SCHEMBL16935935 | 0.76 | HTR2A (0.43) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL28027009 | 0.75 | HTR2A (0.43) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL20201907 | 0.75 | DDR1 (0.41) | HTR2AHTR2CSLC6A2SLC6A4SLC6A3 | |
| SCHEMBL14850384 | 0.75 | ALOX5 (0.41) | — | |
| SCHEMBL21718976 | 0.74 | PTGS1 (0.37) | HTR2ASLC6A2SLC6A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |