Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.37 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | IDO1 | P14902 | 3/20 | 0.34 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.34 |
| ▸ | NR3C2 | P08235 | 3/20 | 0.33 |
| ▸ | HTR2A | P28223 | 2/20 | 0.33 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.33 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.33 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.33 |
| ▸ | FEN1 | P39748 | 1/20 | 0.33 |
| ▸ | NR3C1 | P04150 | 4/20 | 0.31 |
| ▸ | RBP4 | P02753 | 1/20 | 0.31 |
| ▸ | AGXT | P21549 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13437624 | 0.83 | RIPK1 (0.41) | PTGS1PTGS2RIPK1IDO1P2RX7 | |
| SCHEMBL13547861 | 0.82 | PTGS1 (0.40) | PTGS1PTGS2RIPK1IDO1NR3C2 | |
| SCHEMBL12459222 | 0.82 | MPO (0.41) | PTGS1PTGS2RIPK1IDO1NR3C2 | |
| SCHEMBL18176645 | 0.80 | F2RL1 (0.38) | PTGS1PTGS2RIPK1IDO1NR3C2 | |
| SCHEMBL26540975 | 0.79 | PARK7 (0.36) | PTGS1PTGS2RIPK1IDO1NR3C2 | |
| SCHEMBL13547931 | 0.77 | MAPT (0.36) | PTGS1PTGS2RIPK1IDO1P2RX7 | |
| SCHEMBL19732319 | 0.77 | HTR2A (0.39) | PTGS1PTGS2P2RX7NR3C2HTR2A | |
| SCHEMBL14850384 | 0.76 | ALOX5 (0.41) | PTGS2KDM4E | |
| SCHEMBL2625769 | 0.75 | IDO1 (0.42) | PTGS1PTGS2RIPK1IDO1NR3C2 | |
| SCHEMBL12740308 | 0.75 | IDO1 (0.42) | PTGS1PTGS2RIPK1IDO1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | MITSUI CHEMICALS AGRO, INC. (JP) | 2021-11-23 | — | — | US | disclosed |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | MITSUI CHEMICALS AGRO, INC. (JP) | 2020-02-13 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11178870-B2 | Pyridone compounds and agricultural and horticultural fungicides containing the same as active ingredients | PNPO, CYP4X1, PDXK | PTGS1 499/4885PTGS2 1052/4885RIPK1 1569/4885 |
| US-20200045968-A1 | PYRIDONE COMPOUNDS AND AGRICULTURAL AND HORTICULTURAL FUNGICIDES CONTAINING THE SAME AS ACTIVE INGREDIENTS | PNPO, CYP4X1, PDXK | PTGS1 499/4885PTGS2 1052/4885RIPK1 1569/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.