Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 7/20 | 0.38 |
| ▸ | HTR2B | P41595 | 6/20 | 0.38 |
| ▸ | HTR2A | P28223 | 4/20 | 0.38 |
| ▸ | ADRB2 | P07550 | 3/20 | 0.36 |
| ▸ | HTR1A | P08908 | 3/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 3/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CHRM5 | P08912 | 2/20 | 0.35 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.35 |
| ▸ | DRD2 | P14416 | 2/20 | 0.35 |
| ▸ | ADRA2B | P18089 | 2/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20206848 | 0.85 | ACHE (0.41) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL18374457 | 0.82 | HTR2C (0.42) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL20188096 | 0.82 | HTR2C (0.42) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL20338513 | 0.81 | HTR2C (0.43) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| Hydrochloric Acid SCHEMBL20338511 | 0.81 | HTR2C (0.43) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL20201976 | 0.81 | ALDH1A1 (0.38) | HTR2ASLC6A4ALDH1A1KCNH2GAA | |
| SCHEMBL20190702 | 0.80 | HTR2C (0.35) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL20190703 | 0.80 | HTR2C (0.35) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL20201814 | 0.80 | HTR2C (0.37) | HTR2CHTR2BHTR2AADRB2HTR1A | |
| SCHEMBL20190701 | 0.80 | HTR2C (0.35) | HTR2CHTR2BHTR2AADRB2HTR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098204-A1 | 6-MEMBERED URACIL ISOSTERES | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |