Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20207465 | 0.91 | APLNR (0.71) | APLNR | |
| SCHEMBL20207593 | 0.85 | APLNR (0.67) | APLNRPTGS2 | |
| SCHEMBL20189505 | 0.82 | APLNR (0.84) | APLNR | |
| SCHEMBL20188829 | 0.81 | APLNR (1.00) | APLNR | |
| SCHEMBL20207605 | 0.81 | APLNR (0.71) | APLNRPTGS2 | |
| SCHEMBL22537278 | 0.80 | APLNR (0.61) | APLNRPTGS2 | |
| SCHEMBL22537211 | 0.76 | APLNR (0.70) | APLNR | |
| SCHEMBL20207602 | 0.73 | APLNR (0.62) | APLNR | |
| SCHEMBL20188400 | 0.72 | APLNR (0.74) | APLNR | |
| SCHEMBL20207348 | 0.72 | APLNR (0.69) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097945-A1 | HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |