Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22537211 | 0.91 | APLNR (0.70) | APLNR | |
| SCHEMBL20207585 | 0.85 | APLNR (0.68) | APLNRPTGS2 | |
| SCHEMBL20207252 | 0.83 | APLNR (0.69) | APLNR | |
| SCHEMBL17294948 | 0.83 | PTGS2 (0.66) | APLNRPTGS2 | |
| SCHEMBL20207351 | 0.83 | PTGS2 (0.48) | APLNRPTGS2 | |
| SCHEMBL20207348 | 0.82 | APLNR (0.69) | APLNR | |
| SCHEMBL20189255 | 0.81 | APLNR (0.84) | APLNR | |
| SCHEMBL20207350 | 0.81 | APLNR (0.65) | APLNR | |
| SCHEMBL20207275 | 0.80 | APLNR (0.64) | APLNR | |
| SCHEMBL22537233 | 0.80 | APLNR (0.57) | APLNR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3541805-B1 | HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS | AMGEN INC (US) | 2020-10-14 | — | — | EP | disclosed |
| WO-2018097945-A1 | HETEROARYL-SUBSTITUTED TRIAZOLES AS APJ RECEPTOR AGONISTS | AMGEN INC. (US) | 2018-05-31 | — | — | WO | disclosed |