Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.39 |
| ▸ | PTPRC | P08575 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP3 | P42574 | 1/20 | 0.38 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.38 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.38 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21666580 | 0.82 | ALDH1A1 (0.43) | ALDH1A1PTPN1PTPRCL3MBTL1RAB9A | |
| SCHEMBL22752410 | 0.80 | ALDH1A1 (0.46) | ALDH1A1PTPN1PTPRCL3MBTL1RAB9A | |
| SCHEMBL21666421 | 0.80 | ALDH1A1 (0.43) | ALDH1A1PTPN1PTPRCL3MBTL1RAB9A | |
| SCHEMBL15910890 | 0.77 | LMNA (0.54) | ALDH1A1PTPN1PTPRCL3MBTL1CHRM2 | |
| SCHEMBL24904311 | 0.76 | LMNA (0.56) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13313606 | 0.76 | MAOB (0.59) | ALDH1A1L3MBTL1RAB9AMAOBKMT2A | |
| SCHEMBL228601 | 0.74 | NR4A2 (0.51) | ALDH1A1PTPN1PTPRCMAOBKMT2A | |
| SCHEMBL23876180 | 0.74 | KMT2A (0.50) | ALDH1A1PTPN1PTPRCL3MBTL1KMT2A | |
| SCHEMBL23876186 | 0.74 | NPC1 (0.49) | ALDH1A1PTPN1PTPRCL3MBTL1RAB9A | |
| SCHEMBL3045824 | 0.74 | ALDH1A1 (0.49) | ALDH1A1PTPN1PTPRCL3MBTL1TSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018098207-A1 | HYDANTOIN CONTAINING DEOXYURIDINE TRIPHOSPHATASE INHIBITORS | CV6 THERAPEUTICS (NI) LIMITED (GB) | 2018-05-31 | — | — | WO | disclosed |