Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 5/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21666421 | 0.92 | ALDH1A1 (0.43) | ALDH1A1PTPN1CHRM2CHRM4CHRM5 | |
| SCHEMBL22752410 | 0.82 | ALDH1A1 (0.46) | ALDH1A1PTPN1CHRM2CHRM4CHRM5 | |
| SCHEMBL20207722 | 0.82 | ALDH1A1 (0.41) | ALDH1A1PTPN1CHRM2CHRM4CHRM5 | |
| SCHEMBL24722152 | 0.81 | MAOB (0.41) | ALDH1A1PTPN1PTPRCLMNAKMT2A | |
| SCHEMBL15910890 | 0.79 | LMNA (0.54) | ALDH1A1PTPN1CHRM2CHRM4CHRM1 | |
| SCHEMBL12091492 | 0.78 | KMT2A (0.56) | ALDH1A1LMNAKMT2ATDP1L3MBTL1 | |
| SCHEMBL24904311 | 0.78 | LMNA (0.56) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL13313606 | 0.78 | MAOB (0.59) | ALDH1A1LMNAKMT2AL3MBTL1SLC6A2 | |
| SCHEMBL24773109 | 0.76 | POLB (0.52) | ALDH1A1PTPN1CHRM2CHRM4CHRM5 | |
| SCHEMBL23876186 | 0.76 | NPC1 (0.49) | ALDH1A1PTPN1PTPRCLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10550073-B2 | Benzamide derivative | CSPC ZHONGQI PHARMACEUTICAL TECHNOLOGY (SHIJIAZHUANG) CO., LTD. (CN) | 2020-02-04 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10550073-B2 | Benzamide derivative | CYP3A5, ABCB1, CYP2D6 | ALDH1A1 82/4885PTPN1 4238/4885CHRM2 343/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.