Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ERN1 | O75460 | 9/20 | 0.49 |
| ▸ | MTHFD1 | P11586 | 1/20 | 0.45 |
| ▸ | MTHFD2 | P13995 | 1/20 | 0.45 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | DRD2 | P14416 | 1/20 | 0.43 |
| ▸ | DRD4 | P21917 | 1/20 | 0.43 |
| ▸ | DRD3 | P35462 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 8/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21354099 | 0.88 | ERN1 (0.58) | ERN1MTHFD1MTHFD2TMEM97SIGMAR1 | |
| SCHEMBL21417110 | 0.82 | TMEM97 (0.49) | ERN1MTHFD1MTHFD2TMEM97SIGMAR1 | |
| SCHEMBL20208889 | 0.82 | MTHFD1 (0.47) | ERN1MTHFD1MTHFD2DRD2DRD4 | |
| SCHEMBL21354138 | 0.81 | MTHFD1 (0.47) | ERN1MTHFD1MTHFD2DRD2DRD4 | |
| SCHEMBL24691517 | 0.81 | MTHFD1 (0.46) | ERN1MTHFD1MTHFD2DRD2DRD4 | |
| SCHEMBL20208684 | 0.76 | CXCR3 (0.47) | ERN1MTHFD1MTHFD2TMEM97SIGMAR1 | |
| SCHEMBL23949707 | 0.73 | TMEM97 (0.57) | TMEM97SIGMAR1PTGDR2 | |
| SCHEMBL31454878 | 0.72 | ERN1 (0.79) | ERN1MTHFD1MTHFD2DRD4 | |
| SCHEMBL16197809 | 0.71 | ERN1 (0.71) | ERN1MTHFD1MTHFD2DRD2DRD4 | |
| SCHEMBL20208638 | 0.70 | GAA (0.51) | ERN1DRD2DRD4DRD3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097162-A1 | SULFONAMIDE DERIVATIVE HAVING COUMARIN SKELETON | 第一三共株式会社 | 2018-05-31 | — | — | WO | disclosed |