Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | GLA | P06280 | 2/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | CASP1 | P29466 | 2/20 | 0.51 |
| ▸ | CASP7 | P55210 | 2/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.51 |
| ▸ | MAOA | P21397 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.51 |
| ▸ | ERN1 | O75460 | 6/20 | 0.50 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.46 |
| ▸ | DRD2 | P14416 | 3/20 | 0.46 |
| ▸ | DRD3 | P35462 | 3/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20208888 | 0.83 | DRD2 (0.44) | KDM4EALDH1A1HPGDHSD17B10MAOA | |
| SCHEMBL20208640 | 0.70 | ERN1 (0.49) | ERN1DRD4DRD2DRD3 | |
| SCHEMBL20208562 | 0.69 | KDM4E (0.55) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL21276083 | 0.68 | POLB (0.43) | ALDH1A1MAPK1 | |
| SCHEMBL24691517 | 0.68 | MTHFD1 (0.46) | ERN1DRD4DRD2DRD3 | |
| SCHEMBL20208889 | 0.67 | MTHFD1 (0.47) | ERN1DRD4DRD2DRD3 | |
| SCHEMBL17601909 | 0.67 | ERN1 (1.00) | ERN1DRD4DRD2DRD3 | |
| SCHEMBL6937223 | 0.66 | SHBG (0.55) | GAAKDM4EALDH1A1MAPK1SHBG | |
| SCHEMBL31454878 | 0.65 | ERN1 (0.79) | GAAKDM4EALDH1A1GLAHPGD | |
| SCHEMBL20209014 | 0.65 | ERN1 (0.69) | GAAKDM4EALDH1A1GLAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018097162-A1 | SULFONAMIDE DERIVATIVE HAVING COUMARIN SKELETON | 第一三共株式会社 | 2018-05-31 | — | — | WO | disclosed |