Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.41 |
| ▸ | TSHR | P16473 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.39 |
| ▸ | HPGD | P15428 | 2/20 | 0.39 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | GPR3 | P46089 | 2/20 | 0.39 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | NCF1 | P14598 | 1/20 | 0.38 |
| ▸ | MPO | P05164 | 3/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.38 |
| ▸ | THPO | P40225 | 1/20 | 0.38 |
| ▸ | CYP4Z1 | Q86W10 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147219 | 0.76 | SLC9A1 (0.43) | KDM4EHSD17B10TSHRALDH1A1CYP1A2 | |
| SCHEMBL20225759 | 0.74 | MPO (0.40) | KDM4EHSD17B10TSHRALDH1A1HPGD | |
| SCHEMBL19819749 | 0.74 | MPO (0.42) | KDM4EHSD17B10TSHRALDH1A1CYP1A2 | |
| SCHEMBL18294577 | 0.71 | MPO (0.61) | KDM4EALDH1A1CYP1A2HPGDMPO | |
| SCHEMBL17616025 | 0.71 | MPO (0.61) | KDM4EHSD17B10TSHRALDH1A1CYP1A2 | |
| SCHEMBL2914480 | 0.67 | MAPT (0.46) | KDM4EHSD17B10TSHRALDH1A1CYP1A2 | |
| SCHEMBL12926036 | 0.66 | SLC34A1 (0.60) | KDM4EHSD17B10TSHRALDH1A1CYP1A2 | |
| SCHEMBL9927339 | 0.66 | CYP1A2 (0.43) | KDM4ETSHRALDH1A1CYP1A2GPR3 | |
| SCHEMBL3652714 | 0.65 | GLS (0.50) | KDM4EHSD17B10TSHRALDH1A1CYP1A2 | |
| SCHEMBL8682362 | 0.65 | KMT2A (0.43) | KDM4ETSHRALDH1A1HPGDMPO |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180159051-A1 | EMITTERS BASED ON OCTAHEDRAL METAL COMPLEXES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-06-07 | — | — | US | disclosed |
| US-20180148464-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-05-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180159051-A1 | EMITTERS BASED ON OCTAHEDRAL METAL COMPLEXES | POLR1G, ITPA, ERCC5 | KDM4E 4685/4885HSD17B10 4582/4885TSHR 1713/4885 |
| US-20180148464-A1 | TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES | PAICS, DNTT, PNPO | KDM4E 2613/4885HSD17B10 3924/4885TSHR 2799/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.