SCHEMBL20209764

SCHEMBL20209764

CCc1scc(C(C)C)c1N

nearest known ligand 0.33

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25128201 0.77 ELANE (0.34) ELANE
SCHEMBL25653042 0.77 ELANE (0.34) ELANE
SCHEMBL25128692 0.75 GABRA1 (0.37) ELANE
SCHEMBL18721967 0.71 GABRA1 (0.34)
SCHEMBL25971699 0.71
SCHEMBL24924406 0.71 POLB (0.31)
SCHEMBL8182063 0.71 POLB (0.34)
Hydrochloric Acid SCHEMBL29505744 0.70 ALDH1A1 (0.33)
Hydrochloric Acid SCHEMBL9634974 0.70 GABRA1 (0.33)
SCHEMBL3789254 0.67 MAPT (0.34)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11653560-B2 Tetradentate metal complexes with carbon group bridging ligands ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2023-05-16 US disclosed
US-20210126208-A1 Tetradentate Metal Complexes with Carbon Group Bridging Ligands UNIV ARIZONA STATE (US) 2021-04-29 US disclosed
US-10944064-B2 Tetradentate metal complexes with carbon group bridging ligands ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2021-03-09 US disclosed
US-20210024559-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES UNIV ARIZONA STATE (US) 2021-01-28 US disclosed
US-10836785-B2 Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2020-11-17 US disclosed
US-10033003-B2 Tetradentate metal complexes with carbon group bridging ligands ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-07-24 US disclosed
US-10020455-B2 Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY (US) 2018-07-10 US disclosed
US-20180148464-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY 2018-05-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10836785-B2 Tetradentate and octahedral metal complexes containing naphthyridinocarbazole and its analogues PAICS, DNTT, PNPO ELANE 1761/4885
US-20210126208-A1 Tetradentate Metal Complexes with Carbon Group Bridging Ligands STAU1, POLR1G, CLTC ELANE 1867/4885
US-10033003-B2 Tetradentate metal complexes with carbon group bridging ligands STAU1, POLR1G, CLTC ELANE 1867/4885
US-10944064-B2 Tetradentate metal complexes with carbon group bridging ligands STAU1, POLR1G, CLTC ELANE 1867/4885
US-11653560-B2 Tetradentate metal complexes with carbon group bridging ligands PDCD2L, STAU1, POLR1G ELANE 2484/4885
US-10020455-B2 Tetradentate platinum and palladium complex emitters containing phenyl-pyrazole and its analogues PDCD1, PDCD11, HPRT1 ELANE 2338/4885
US-20180148464-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES PAICS, DNTT, PNPO ELANE 1761/4885
US-20210024559-A1 TETRADENTATE AND OCTAHEDRAL METAL COMPLEXES CONTAINING NAPHTHYRIDINOCARBAZOLE AND ITS ANALOGUES PAICS, DNTT, PNPO ELANE 1761/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.