SCHEMBL20209892

SCHEMBL20209892

Cc1ccccc1N(c1cccc2c1oc1ccccc12)c1cc2c(c3c1oc1ccccc13)-c1cc3c(cc1C21c2ccccc2-c2ccccc21)-c1c(cc(N(c2ccccc2C)c2cccc4c2oc2ccccc24)c2oc4ccccc4c12)C31c2ccccc2-c2ccccc21

nearest known ligand 0.34

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
▸ ALOX5 P09917 2/20 0.34
▸ PGR P06401 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20210076 0.95 ESR1 (0.32) ALOX5
SCHEMBL20210012 0.90 — —
SCHEMBL20210008 0.89 — —
SCHEMBL20209883 0.88 ALOX5 (0.35) ALOX5
SCHEMBL20210070 0.87 PGR (0.35) ALOX5PGR
SCHEMBL27250221 0.87 ALOX5 (0.37) ALOX5PGR
SCHEMBL20210013 0.86 LMNA (0.31) —
SCHEMBL20209890 0.84 — —
SCHEMBL20210358 0.84 PGR (0.33) PGR
SCHEMBL20210056 0.83 ALOX5 (0.33) ALOX5PGR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) MERCK PATENT GMBH (DE) 2023-02-21 — — US disclosed
EP-3544984-B1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2020-12-23 — — EP disclosed
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2019-10-17 — — US disclosed
WO-2018095888-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) MERCK PATENT GMBH (DE) 2018-05-31 — — WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20190315764-A1 BISBENZOFURAN-FUSED 2,8-DIAMINOINDENO[1,2-B]FLUORENE DERIVATIVES AND RELATED COMPOUNDS AS MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES (OLED) OCIAD1, OCIAD2, AOC1 ALOX5 514/4885PGR 4601/4885
US-11584753-B2 Bisbenzofuran-fused 2,8-diaminoindeno[1,2-b]fluorene derivatives and related compounds as materials for organic electroluminescent devices (OLED) OCIAD1, OCIAD2, AOC1 ALOX5 514/4885PGR 4601/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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