Known targets — ChEMBL curated mechanism
MMP1MMP13MMP7MMP8polrplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Alcohol. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.61 |
| ▸ | TAAR1 | Q96RJ0 | 6/20 | 0.54 |
| ▸ | HTR3A | P46098 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.52 |
| ▸ | APEX1 | P27695 | 1/20 | 0.52 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.52 |
| ▸ | AOC3 | Q16853 | 5/20 | 0.52 |
| ▸ | HTR2A | P28223 | 1/20 | 0.50 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.48 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.48 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL147501 | 0.91 | TAAR1 (0.62) | LMNATAAR1HTR3ATSHRNFKB1 | |
| SCHEMBL2021 | 0.91 | TAAR1 (0.62) | LMNATAAR1HTR3ATSHRNFKB1 | |
| SCHEMBL175554 | 0.91 | TAAR1 (0.62) | LMNATAAR1HTR3ATSHRNFKB1 | |
| Alcohol SCHEMBL27579663 | 0.89 | LMNA (0.50) | LMNATAAR1HTR3ATSHRNFKB1 | |
| Ammonia Solution, Strong SCHEMBL27544022 | 0.89 | TAAR1 (0.60) | LMNATAAR1HTR3ATSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL8178381 | 0.89 | KDM4E (0.64) | LMNATAAR1HTR3ATSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL7153880 | 0.89 | KDM4E (0.64) | LMNATAAR1HTR3ATSHRNFKB1 | |
| Bromide SCHEMBL29131747 | 0.89 | TAAR1 (0.60) | LMNATAAR1HTR3ATSHRNFKB1 | |
| Hydrochloric Acid SCHEMBL29175850 | 0.89 | KDM4E (0.64) | LMNATAAR1HTR3ATSHRNFKB1 | |
| SCHEMBL8339683 | 0.87 | TAAR1 (0.56) | LMNATAAR1HTR3ATSHRNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011032640-A2 | ALKOXYLATED TRIALKANOL AMINE CONDENSATES AND THE USE THEREOF AS DEMULSIFIERS | CLARIANT INTERNATIONAL LTD (CH) | 2011-03-24 | — | — | WO | disclosed |