Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 2/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.62 |
| ▸ | THRB | P10828 | 1/20 | 0.62 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.62 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.58 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
| ▸ | GLA | P06280 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.56 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 1/20 | 0.55 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.54 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.54 |
| ▸ | MDM4 | O15151 | 1/20 | 0.54 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.54 |
| ▸ | GFER | P55789 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11940456 | 1.00 | ATM (0.63) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL12863012 | 1.00 | ATM (0.63) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL12563723 | 0.88 | ATM (0.60) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL23170061 | 0.88 | CTSG (0.53) | ATMPOLBGAARAB9A | |
| SCHEMBL30402446 | 0.88 | ATM (0.54) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL12863003 | 0.87 | MDM4 (0.60) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL5693509 | 0.87 | ATM (0.62) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL13900785 | 0.87 | ATM (0.62) | ATMALDH1A1CYP2C9CYP2C19THRB | |
| SCHEMBL30401614 | 0.86 | BIRC2 (0.60) | ALDH1A1CYP2C9CYP2C19THRBHSD17B10 | |
| SCHEMBL12863002 | 0.86 | NPSR1 (0.69) | KMT2AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3551639-B1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-08-23 | — | — | EP | disclosed |
| EP-3551639-B1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INT (DE) | 2023-08-23 | — | — | EP | disclosed |
| EP-3551639-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | Boehringer Ingelheim International GmbH (DE) | 2019-10-16 | — | — | EP | disclosed |
| US-10196413-B2 | Chiral dihydrobenzoazaphosphole ligands and synthesis thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-02-05 | — | — | US | disclosed |
| US-10196413-B2 | Chiral dihydrobenzoazaphosphole ligands and synthesis thereof | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2019-02-05 | — | — | US | disclosed |
| WO-2018106621-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-14 | — | — | WO | disclosed |
| WO-2018106621-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-14 | — | — | WO | disclosed |
| US-20180155377-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-07 | — | — | US | disclosed |
| US-20180155377-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-07 | — | — | US | disclosed |
| US-20180155377-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155377-A1 | NOVEL CHIRAL DIHYDROBENZOAZAPHOSPHOLE LIGANDS AND SYNTHESIS THEREOF | FDPS, GNPAT, PPIP5K2 | ATM 4517/4885ALDH1A1 1332/4885CYP2C9 2507/4885 |
| US-10196413-B2 | Chiral dihydrobenzoazaphosphole ligands and synthesis thereof | DHODH, FDPS, GNPAT | ATM 4577/4885ALDH1A1 1159/4885CYP2C9 2092/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.