SCHEMBL27750743

SCHEMBL27750743

NC(=O)c1n[nH]c2ccccc12

nearest known ligand 0.62

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 5/20 0.62
YTHDC1 Q96MU7 1/20 0.62
STAT3 P40763 1/20 0.62
HIF1A Q16665 1/20 0.62
FLT3 P36888 2/20 0.58
CDK2 P24941 2/20 0.58
CCNA2 P20248 1/20 0.58
CCNA1 P78396 1/20 0.58
CTNNB1 P35222 3/20 0.57
WNT3A P56704 3/20 0.57
IDO1 P14902 1/20 0.55
PDPK1 O15530 1/20 0.53
CYP3A4 P08684 1/20 0.53
GAA P10253 1/20 0.53
NPC1 O15118 4/20 0.53
RAB9A P51151 3/20 0.53
EPHB3 P54753 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.51
ALDH1A1 P00352 1/20 0.51
CSNK2A1 P68400 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL82761 1.00 KDM4E (0.62) KDM4EYTHDC1STAT3HIF1AFLT3
Hydrochloric Acid SCHEMBL2175299 0.98 KDM4E (0.60) KDM4EYTHDC1STAT3HIF1AFLT3
Hydrochloric Acid SCHEMBL30404733 0.98 KDM4E (0.60) KDM4EYTHDC1STAT3HIF1AFLT3
Hydrochloric Acid SCHEMBL29962256 0.98 KDM4E (0.60) KDM4EYTHDC1STAT3HIF1AFLT3
Hydrochloric Acid SCHEMBL5071439 0.98 KDM4E (0.60) KDM4EYTHDC1STAT3HIF1AFLT3
Oxalic Acid SCHEMBL6033591 0.95 FLT3 (0.58) KDM4EYTHDC1STAT3HIF1AFLT3
Formic Acid SCHEMBL5987899 0.93 KDM4E (0.55) KDM4EYTHDC1STAT3HIF1AFLT3
Trifluoroacetic Acid SCHEMBL15546473 0.90 FLT3 (0.54) KDM4EYTHDC1STAT3HIF1AFLT3
SCHEMBL1962245 0.87 CYP1A2 (0.54) KDM4EYTHDC1STAT3HIF1AFLT3
SCHEMBL28388762 0.86 KDM4E (0.49) KDM4EYTHDC1STAT3HIF1AFLT3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4301736-B1 MACROCYCLIC COMPOUNDS AS PROTEASOME SUBUNIT BETA TYPE-5 INHIBITORS LEAD DISCOVERY CENTER GMBH (DE) 2025-10-08 EP claimed
EP-4186894-B1 FGFR INHIBITOR COMPOUND AND USE THEREOF HENAN MEDINNO PHARMACEUTICAL TECH CO LTD (CN) 2024-12-04 EP claimed
EP-4460301-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES Universität zu Köln (DE) 2024-11-13 EP claimed
WO-2023131576-A1 SIGNALLING-PATHWAY INHIBITOR COMBINATIONS FOR USE IN THE TREATMENT OF CANCER DISEASES UNIVERSITÄT ZU KÖLN (DE) 2023-07-13 WO claimed
EP-3275440-B1 NOVEL OXADIAZOLE DERIVATIVE AND PHARMACEUTICAL CONTAINING SAME NAT CT GERIATRICS & GERONTOLOGY (JP) 2022-05-04 EP claimed
EP-4654964-A1 SULFONE-1H-PYRROLE-2-CARBOXAMIDE INHIBITORS OF SARS-COV-2 NSP14 METHYLTRANSFERASE AND DERIVATIVES THEREOF The Rockefeller University (US) 2025-12-03 EP disclosed
EP-4593822-A2 NOVEL GPX4 INHIBITORS AND USES THEREOF The Trustees Of Columbia University In The City Of New York (US) 2025-08-06 EP disclosed
WO-2025133961-A1 NITROGEN-CONTAINING HETEROARYL COMPOUNDS FOR THE TREATMENT OF CHRONIC DISEASES PFIZER INC. (US) 2025-06-26 WO disclosed
CN-120202195-A Substitution as fungicides benzodiazepines of (C) 巴斯夫欧洲公司 2025-06-24 CN disclosed
CN-120202196-A Substitution as fungicides benzodiazepines of (C) 巴斯夫欧洲公司 2025-06-24 CN disclosed
CN-120091993-A Use of strobilurin type compounds for combating phytopathogenic fungi comprising the amino acid substitution F129L in the mitochondrial cytochrome b protein conferring resistance to Qo inhibitor XV 巴斯夫欧洲公司 2025-06-03 CN disclosed
CN-119789874-A Cannabis for targeted delivery vegetable dendrimer composition 约翰霍普金斯大学 2025-04-08 CN disclosed
EP-4031214-A1 INJECTION SYSTEMS AND METHODS OF THEIR USE Bullseye Therapeutics, Inc. (US) 2022-07-27 EP disclosed
CN-114467956-A Pesticide composition containing indoxacarb and application thereof 青岛奥迪斯生物科技有限公司 2022-05-13 CN disclosed
CN-114467956-A Pesticide composition containing indoxacarb and application thereof 青岛奥迪斯生物科技有限公司 2022-05-13 CN disclosed
EP-3790873-B1 1H-INDAZOLE-3-CARBOXAMIDE COMPOUNDS AS GLYCOGEN SYNTHASE KINASE 3 BETA INHIBITORS ACRAF (IT) 2022-04-27 EP disclosed
CN-108366563-B Herbicide mixture and preparation for potatoes 阿达玛阿甘有限公司 2022-03-25 CN disclosed
WO-2022036256-A1 MOTORIZED INJECTION SYSTEM AND METHODS OF USE BULLSEYE THERAPEUTICS, INC. (US) 2022-02-17 WO disclosed
EP-3411411-B3 1H-INDAZOLE-3-CARBOXAMIDE DERIVATIVES AND RELATED COMPOUNDS AS FACTOR D INHIBITORS FOR TREATING DISEASES CHARACTERIZED BY ABERRANT COMPLEMENT SYSTEM ACTIVITY, SUCH AS E.G. IMMUNOLOGICAL DISORDERS BIOCRYST PHARM INC (US) 2022-01-26 EP disclosed
CN-101370784-A Polycyclic indazole derivatives that are erk inhibitors SCHERING CORP (US) 2009-02-18 CN disclosed