Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 3/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PTPN11 | Q06124 | 1/20 | 0.40 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPC1 | O15118 | 4/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.39 |
| ▸ | EED | O75530 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.38 |
| ▸ | NAMPT | P43490 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | SORT1 | Q99523 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217630 | 0.80 | RAB9A (0.45) | RAB9AMEN1KMT2AHPGDNPC1 | |
| SCHEMBL20217804 | 0.80 | RAB9A (0.43) | RAB9ASMN1; SMN2MEN1KMT2ANPC1 | |
| SCHEMBL20217623 | 0.77 | HPGD (0.45) | RAB9AHPGDNPC1LMNANAMPT | |
| SCHEMBL20217341 | 0.70 | CYP3A4 (0.40) | RAB9AHPGDNPC1ALDH1A1LMNA | |
| SCHEMBL20217432 | 0.70 | KMT2A (0.47) | RAB9ASMN1; SMN2MEN1KMT2AHPGD | |
| SCHEMBL20217777 | 0.70 | KMT2A (0.49) | RAB9ASMN1; SMN2KMT2APTPN11NPC1 | |
| SCHEMBL20217644 | 0.70 | KMT2A (0.45) | RAB9ASMN1; SMN2MEN1KMT2APTPN11 | |
| SCHEMBL20217401 | 0.70 | KDM4E (0.44) | RAB9ASMN1; SMN2MEN1KMT2APTPN11 | |
| SCHEMBL20217423 | 0.69 | KDM4E (0.40) | RAB9AMEN1KMT2AHPGDNPC1 | |
| SCHEMBL20217816 | 0.68 | RAB9A (0.44) | RAB9AMEN1KMT2ANPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |