Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 4/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.42 |
| ▸ | TTK | P33981 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
| ▸ | NAMPT | P43490 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.40 |
| ▸ | MELK | Q14680 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217341 | 0.91 | CYP3A4 (0.40) | RAB9ACYP3A4TTKAURKBINCENP | |
| SCHEMBL20217630 | 0.90 | RAB9A (0.45) | RAB9AKDM4ECYP3A4TTKAURKB | |
| SCHEMBL20217423 | 0.84 | KDM4E (0.40) | RAB9AKDM4ECYP3A4NPC1LMNA | |
| SCHEMBL20217636 | 0.82 | NAMPT (0.39) | CA2NAMPTMAPK1ROCK2 | |
| SCHEMBL20217434 | 0.80 | RAB9A (0.40) | RAB9AKDM4ENPC1LMNAPOLB | |
| SCHEMBL20217432 | 0.80 | KMT2A (0.47) | RAB9AKDM4ECYP3A4NPC1LMNA | |
| SCHEMBL20217777 | 0.79 | KMT2A (0.49) | RAB9AKDM4ECYP3A4NPC1LMNA | |
| SCHEMBL20217644 | 0.79 | KMT2A (0.45) | RAB9AKDM4ECYP3A4NPC1LMNA | |
| SCHEMBL20217401 | 0.79 | KDM4E (0.44) | RAB9AKDM4ECYP3A4NPC1LMNA | |
| SCHEMBL20217510 | 0.77 | NAMPT (0.42) | RAB9AKDM4ECYP3A4NPC1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |