Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | TTK | P33981 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | INCENP | Q9NQS7 | 1/20 | 0.40 |
| ▸ | HSP90AA1 | P07900 | 5/20 | 0.35 |
| ▸ | HSP90AB1 | P08238 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | KLKB1 | P03952 | 6/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.33 |
| ▸ | VNN1 | O95497 | 1/20 | 0.33 |
| ▸ | PPARG | P37231 | 1/20 | 0.32 |
| ▸ | NAMPT | P43490 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217804 | 0.91 | RAB9A (0.43) | CYP3A4TTKAURKBINCENPRAB9A | |
| SCHEMBL20217636 | 0.82 | NAMPT (0.39) | HSP90AA1HSP90AB1KLKB1NAMPT | |
| SCHEMBL20217630 | 0.80 | RAB9A (0.45) | CYP3A4TTKAURKBINCENPRAB9A | |
| SCHEMBL20217587 | 0.78 | CYP3A4 (0.37) | CYP3A4TTKAURKBINCENPHSP90AA1 | |
| SCHEMBL20217529 | 0.77 | L3MBTL1 (0.45) | CYP3A4RAB9AALDH1A1LMNA | |
| SCHEMBL20217423 | 0.75 | KDM4E (0.40) | CYP3A4RAB9ANPC1ALDH1A1LMNA | |
| SCHEMBL20217623 | 0.75 | HPGD (0.45) | RAB9AKLKB1NPC1LMNAHPGD | |
| SCHEMBL20217365 | 0.74 | RXFP1 (0.44) | CYP3A4TTKAURKBINCENPALDH1A1 | |
| SCHEMBL20217515 | 0.71 | ALDH1A1 (0.39) | HSP90AA1HSP90AB1KLKB1ALDH1A1LMNA | |
| SCHEMBL20217434 | 0.70 | RAB9A (0.40) | RAB9ANPC1ALDH1A1LMNAHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |