Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | REN | P00797 | 1/20 | 0.36 |
| ▸ | CTSD | P07339 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 2/20 | 0.35 |
| ▸ | PLAU | P00749 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217462 | 0.89 | MAPT (0.38) | ALDH1A1POLBKMT2ALMNATP53 | |
| SCHEMBL20217846 | 0.79 | CYP3A4 (0.49) | ALDH1A1MEN1KMT2A | |
| SCHEMBL20217515 | 0.78 | ALDH1A1 (0.39) | ALDH1A1PKMPOLBMEN1KMT2A | |
| SCHEMBL20217667 | 0.77 | CNR2 (0.42) | ALDH1A1POLBKMT2AHPGDRAB9A | |
| SCHEMBL20217393 | 0.76 | ALDH1A1 (0.57) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL20217767 | 0.74 | CYP3A4 (0.38) | — | |
| SCHEMBL20217479 | 0.73 | MAPK1 (0.43) | ALDH1A1MEN1KMT2AHPGDRAB9A | |
| SCHEMBL20217365 | 0.71 | RXFP1 (0.44) | ALDH1A1POLBMEN1KMT2ALMNA | |
| SCHEMBL20217630 | 0.70 | RAB9A (0.45) | ALDH1A1PKMPOLBMEN1KMT2A | |
| SCHEMBL20217657 | 0.70 | HSD17B10 (0.45) | MEN1KMT2AHPGDHSD17B10KDM1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |