Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 5/20 | 0.41 |
| ▸ | TTK | P33981 | 5/20 | 0.41 |
| ▸ | AURKB | Q96GD4 | 5/20 | 0.41 |
| ▸ | INCENP | Q9NQS7 | 5/20 | 0.41 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.36 |
| ▸ | WDR91 | A4D1P6 | 1/20 | 0.33 |
| ▸ | F10 | P00742 | 2/20 | 0.32 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.32 |
| ▸ | BMPR1B | O00238 | 1/20 | 0.32 |
| ▸ | BMPR1A | P36894 | 1/20 | 0.32 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.32 |
| ▸ | ACVRL1 | P37023 | 1/20 | 0.32 |
| ▸ | ACVR1 | Q04771 | 1/20 | 0.32 |
| ▸ | AKT1 | P31749 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | SMYD3 | Q9H7B4 | 2/20 | 0.31 |
| ▸ | WDR5 | P61964 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217446 | 0.80 | CYP3A4 (0.53) | CYP3A4TTKAURKBINCENPTRPM8 | |
| SCHEMBL20217484 | 0.79 | CYP3A4 (0.65) | CYP3A4TTKAURKBINCENPTRPM8 | |
| SCHEMBL20217633 | 0.79 | TRPM8 (0.43) | CYP3A4TTKAURKBINCENPTRPM8 | |
| SCHEMBL20217332 | 0.79 | TRPM8 (0.43) | CYP3A4TTKAURKBINCENPTRPM8 | |
| SCHEMBL16292138 | 0.78 | TTK (0.66) | CYP3A4TTKAURKBINCENP | |
| SCHEMBL16292137 | 0.78 | TTK (0.66) | CYP3A4TTKAURKBINCENP | |
| SCHEMBL20217432 | 0.78 | KMT2A (0.47) | CYP3A4MEN1ALDH1A1MAPK1KMT2A | |
| SCHEMBL20217641 | 0.77 | CYP3A4 (0.47) | CYP3A4TTKAURKBINCENPWDR91 | |
| SCHEMBL20217349 | 0.76 | CYP3A4 (0.50) | CYP3A4TTKAURKBINCENPTRPM8 | |
| SCHEMBL20217579 | 0.76 | CYP3A4 (0.65) | CYP3A4TTKAURKBINCENPWDR5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |