Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 1/20 | 0.42 |
| ▸ | CCR3 | P51677 | 1/20 | 0.42 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.42 |
| ▸ | F10 | P00742 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.42 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.42 |
| ▸ | F7 | P08709 | 1/20 | 0.42 |
| ▸ | F3 | P13726 | 1/20 | 0.42 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.42 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SLC5A7 | Q9GZV3 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20217340 | 0.87 | MEN1 (0.42) | HRH1CCR3KCNH2F10F2 | |
| SCHEMBL20217305 | 0.85 | HSD17B10 (0.49) | F10SLC5A7ALDH1A1LMNAMEN1 | |
| SCHEMBL20217221 | 0.83 | TTK (0.51) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217681 | 0.82 | L3MBTL1 (0.40) | HRH1CCR3KCNH2F10F2 | |
| SCHEMBL20217729 | 0.82 | F10 (0.44) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217304 | 0.82 | F10 (0.44) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217290 | 0.81 | ALDH1A1 (0.49) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217747 | 0.79 | CYP3A4 (0.47) | F10F2PRSS1PRSS2F7 | |
| SCHEMBL20217564 | 0.79 | LMNA (0.43) | HRH1CCR3KCNH2SRD5A1SLC5A7 | |
| SCHEMBL20217682 | 0.79 | HRH3 (0.41) | HRH1CCR3KCNH2F10F2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2766352-B1 | INDAZOLE COMPOUNDS AS KINASE INHIBITORS AND METHOD OF TREATING CANCER WITH SAME | UNIV HEALTH NETWORK UHN (CA) | 2018-06-06 | — | — | EP | disclosed |