SCHEMBL2022016

SCHEMBL2022016

c1ccc(-c2ccc3c(-c4ccc(-c5cccnc5)nc4)c4ccccc4c(-c4ccc(-c5cccnc5)nc4)c3c2)cc1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP19A1 P11511 2/20 0.49
CYP2A6 P11509 4/20 0.48
CYP3A4 P08684 4/20 0.48
PIM1 P11309 2/20 0.46
PIM3 Q86V86 1/20 0.46
PIM2 Q9P1W9 1/20 0.46
DHODH Q02127 1/20 0.45
CYP11B1 P15538 4/20 0.43
CYP11B2 P19099 3/20 0.43
CYP17A1 P05093 1/20 0.42
CYP1A2 P05177 2/20 0.41
LMNA P02545 1/20 0.41
RAF1 P04049 1/20 0.41
MAPK1 P28482 1/20 0.41
HIF1A Q16665 1/20 0.41
MKNK1 Q9BUB5 1/20 0.41
MKNK2 Q9HBH9 1/20 0.41
CHEK1 O14757 1/20 0.41
CYP2D6 P10635 2/20 0.40
CYP2C9 P11712 2/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11886867 0.99 CYP19A1 (0.48) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL15977582 0.96 CYP19A1 (0.48) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL13759440 0.94 CYP2A6 (0.48) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL17589453 0.94 CYP2A6 (0.56) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL17019481 0.94 CYP2A6 (0.56) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL17463152 0.94 CYP2A6 (0.56) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL15977512 0.93 CYP19A1 (0.49) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL15977539 0.92 CYP11B1 (0.47) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL14849190 0.90 CYP11B1 (0.49) CYP19A1CYP2A6CYP3A4PIM1PIM3
SCHEMBL13145249 0.90 CYP11B1 (0.50) CYP19A1CYP2A6CYP3A4PIM1DHODH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 43 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2019-07-11 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
US-9954169-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2018-04-24 US disclosed
EP-2669262-B1 NOVEL ANTHRACENE COMPOUND AND ORGANIC ELECTROLUMINESCENCE ELEMENT USING SAME JNC CORP (JP) 2018-03-07 EP disclosed
US-20180047913-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE JNC CORPORATION (JP) 2018-02-15 US disclosed
US-9860960-B2 Organic EL display device and method for production of the same JOLED INC. (JP) 2018-01-02 US disclosed
US-9590182-B2 Benzofluorene compound, material for luminescent layer using said compound and organic electroluminescent device JNC CORPORATION (JP) 2017-03-07 US disclosed
US-9478750-B2 Anthracene derivative and organic electroluminescent element using the same JNC CORPORATION (JP) 2016-10-25 US disclosed
US-9105847-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2015-08-11 US disclosed
US-9105847-B2 Organic EL display and method of manufacturing the same JOLED INC. (JP) 2015-08-11 US disclosed
US-20110215310-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SK MATERIALS JNC CO., LTD. (KR) 2011-09-08 US disclosed
US-20110215310-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SK MATERIALS JNC CO., LTD. (KR) 2011-09-08 US disclosed
US-20110215310-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SK MATERIALS JNC CO., LTD. (KR) 2011-09-08 US disclosed
US-7964293-B2 Electron transport material and organic electroluminescent device using the same JNC CORPORATION (JP) 2011-06-21 US disclosed
US-7964293-B2 Electron transport material and organic electroluminescent device using the same JNC CORPORATION (JP) 2011-06-21 US disclosed
US-7964293-B2 Electron transport material and organic electroluminescent device using the same JNC CORPORATION (JP) 2011-06-21 US disclosed
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SK MATERIALS JNC CO., LTD. (KR) 2009-05-28 US disclosed
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SK MATERIALS JNC CO., LTD. (KR) 2009-05-28 US disclosed
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SK MATERIALS JNC CO., LTD. (KR) 2009-05-28 US disclosed
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device JNC CORPORATION (JP) 2008-07-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110215310-A1 ELECTRON TRANSPORT MATERIAL AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME SLC25A11, ELAVL1, SLC26A3 CYP19A1 3499/4885CYP2A6 4405/4885CYP3A4 1526/4885
US-20080160347-A1 Benzofluorene compound, emission materials and organic electroluminescent device LEF1, TRPA1, BRD8 CYP19A1 592/4885CYP2A6 2384/4885CYP3A4 418/4885
US-20180047913-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE L1CAM, VDAC1, VDAC2 CYP19A1 2633/4885CYP2A6 3878/4885CYP3A4 1901/4885
US-20190214575-A1 MATERIAL FOR ORGANIC ELECTROLUMINESCENT ELEMENTS, ORGANIC ELECTROLUMINESCENT ELEMENT, DISPLAY DEVICE, AND LIGHTING DEVICE L1CAM, VDAC1, VDAC2 CYP19A1 2633/4885CYP2A6 3878/4885CYP3A4 1901/4885
US-20090134780-A1 Electron transport material and organic electroluminescent device using the same SLC25A11, ELAVL1, SLC26A3 CYP19A1 3499/4885CYP2A6 4405/4885CYP3A4 1526/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.