Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLK1 | P53350 | 3/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | TAS1R3 | Q7RTX0 | 1/20 | 0.41 |
| ▸ | TAS1R1 | Q7RTX1 | 1/20 | 0.41 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.40 |
| ▸ | LPL | P06858 | 1/20 | 0.40 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | HPGD | P15428 | 2/20 | 0.38 |
| ▸ | POLB | P06746 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | APAF1 | O14727 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13514002 | 0.81 | PLK1 (0.47) | PLK1ALDH1A1SMN1; SMN2TDP1TAS1R3 | |
| SCHEMBL18457376 | 0.78 | TAS1R3 (0.45) | PLK1ALDH1A1SMN1; SMN2TDP1TAS1R3 | |
| SCHEMBL22538786 | 0.78 | SIGMAR1 (0.57) | PLK1ALDH1A1SMN1; SMN2LMNAHPGD | |
| SCHEMBL24326627 | 0.77 | ACACB (0.38) | PLK1 | |
| SCHEMBL20860913 | 0.77 | TAS1R3 (0.66) | PLK1ALDH1A1SMN1; SMN2TAS1R3TAS1R1 | |
| SCHEMBL6546242 | 0.77 | ALDH1A1 (0.56) | PLK1ALDH1A1SMN1; SMN2TDP1TAS1R3 | |
| SCHEMBL28470841 | 0.76 | ALDH1A1 (0.52) | PLK1ALDH1A1SMN1; SMN2TDP1TAS1R3 | |
| SCHEMBL23981732 | 0.75 | SMN1; SMN2 (0.44) | PLK1ALDH1A1SMN1; SMN2TDP1TAS1R3 | |
| SCHEMBL23935701 | 0.75 | PLK1 (0.42) | PLK1ALDH1A1SMN1; SMN2CYP2A6GAA | |
| SCHEMBL12309813 | 0.75 | PLK1 (0.46) | PLK1ALDH1A1SMN1; SMN2TDP1TAS1R3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793578-B1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-06-06 | — | — | EP | disclosed |