Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK1 | Q15118 | 1/20 | 0.35 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.35 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | HPGD | P15428 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20220014 | 0.88 | PDK1 (0.37) | PDK1PDK2PDK3PDK4MAPT | |
| SCHEMBL17811805 | 0.81 | L3MBTL1 (0.41) | MAPTHPGDKMT2AMEN1ALOX12 | |
| SCHEMBL15823851 | 0.79 | PTPRC (0.38) | MAPTTP53LMNAALDH1A1POLB | |
| SCHEMBL15058765 | 0.79 | CYP3A4 (0.42) | HPGDGAAALOX15HSD17B10ALDH1A1 | |
| SCHEMBL20194050 | 0.78 | LDHA (0.35) | PDK2MAPTKMT2AMEN1LMNA | |
| SCHEMBL20220175 | 0.78 | GAA (0.34) | KMT2AGAA | |
| SCHEMBL28149572 | 0.78 | LMNA (0.40) | HPGDKMT2AMEN1TP53LMNA | |
| SCHEMBL17325396 | 0.76 | GAA (0.42) | KMT2AGAA | |
| SCHEMBL23902126 | 0.76 | LMNA (0.42) | MAPTHPGDKMT2AMEN1ALOX12 | |
| SCHEMBL16976330 | 0.76 | PDK1 (0.37) | PDK1PDK2PDK3PDK4MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2793578-B1 | N-ARYLAMIDINE-SUBSTITUTED TRIFLUOROETHYLSULFIDE DERIVATIVES AS ACARICIDES AND INSECTICIDES | BAYER CROPSCIENCE AG (DE) | 2018-06-06 | — | — | EP | disclosed |