Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.37 |
| ▸ | ADK | P55263 | 3/20 | 0.35 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20938192 | 0.87 | ALDH1A1 (0.43) | LMNAALDH1A1ALBMAPK1ADK | |
| SCHEMBL26213918 | 0.81 | LMNA (0.37) | LMNAALDH1A1ALBMAPK1SMN1; SMN2 | |
| SCHEMBL20224942 | 0.80 | LMNA (0.60) | LMNASMN1; SMN2ADK | |
| SCHEMBL22990432 | 0.80 | ADK (0.54) | LMNAALDH1A1ADKSLC29A1 | |
| SCHEMBL22990413 | 0.80 | ALDH1A1 (0.64) | LMNAALDH1A1ALBMAPK1SMN1; SMN2 | |
| SCHEMBL24166706 | 0.80 | ADK (0.54) | LMNAALDH1A1ADKSLC29A1 | |
| SCHEMBL21137753 | 0.80 | ADK (0.54) | LMNAALDH1A1ADKSLC29A1 | |
| SCHEMBL23989399 | 0.80 | ADK (0.54) | LMNAALDH1A1ADKSLC29A1 | |
| SCHEMBL23211481 | 0.80 | ADK (0.54) | LMNAALDH1A1ADKSLC29A1 | |
| SCHEMBL18510882 | 0.80 | ADK (0.54) | LMNAALDH1A1ADKSLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4242212-A2 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | Takeda Pharmaceutical Company Limited (JP) | 2023-09-13 | — | — | EP | disclosed |
| WO-2019180683-A1 | STING MODULATOR COMPOUNDS WITH SULFAMATE LINKAGES, AND METHODS OF MAKING AND USING | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2019-09-26 | — | — | WO | disclosed |
| WO-2018100558-A2 | CYCLIC DINUCLEOTIDE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2018-06-07 | — | — | WO | disclosed |