SCHEMBL20224909

SCHEMBL20224909

Nc1ncnc2c1ncn2[C@@H]1O[C@H](COP(=O)(O)O[C@@H]2[C@H](O)[C@@H](COP(=O)(O)O)O[C@H]2n2cc(F)c3c(=O)[nH]cnc32)C[C@H]1F

nearest known ligand 0.64

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
▸ RNASEL Q05823 13/20 0.63

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22872953 0.90 RNASEL (0.49) RNASEL
SCHEMBL22990412 0.90 FUT5 (0.52) RNASEL
SCHEMBL20224914 0.86 RNASEL (0.58) RNASEL
SCHEMBL22990422 0.85 RNASEL (0.43) RNASEL
SCHEMBL20224911 0.83 RNASEL (0.55) RNASEL
SCHEMBL21132977 0.83 RNASEL (0.68) RNASEL
SCHEMBL21417134 0.82 RNASEL (0.70) RNASEL
SCHEMBL20224827 0.82 RNASEL (0.53) RNASEL
SCHEMBL22990366 0.81 RNASEL (0.45) RNASEL
SCHEMBL21417372 0.81 RNASEL (0.66) RNASEL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2018100558-A2 CYCLIC DINUCLEOTIDE TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) 2018-06-07 — — WO disclosed
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