Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HDAC3 | O15379 | 2/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.53 |
| ▸ | STAMBP | O95630 | 1/20 | 0.51 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.49 |
| ▸ | HPGDS | O60760 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.48 |
| ▸ | DRD2 | P14416 | 3/20 | 0.48 |
| ▸ | DRD3 | P35462 | 3/20 | 0.48 |
| ▸ | HTR1A | P08908 | 1/20 | 0.48 |
| ▸ | HTR2A | P28223 | 1/20 | 0.48 |
| ▸ | HTR2C | P28335 | 1/20 | 0.48 |
| ▸ | BCAT1 | P54687 | 1/20 | 0.47 |
| ▸ | CFTR | P13569 | 1/20 | 0.47 |
| ▸ | MGAM | O43451 | 1/20 | 0.47 |
| ▸ | TNKS | O95271 | 1/20 | 0.46 |
| ▸ | PPARD | Q03181 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6741897 | 0.80 | MGAM (0.60) | KDM4EALDH1A1HPGDSMN1; SMN2BCAT1 | |
| SCHEMBL20224973 | 0.79 | L3MBTL1 (0.53) | HDAC3HDAC1HDAC2KDM4EALDH1A1 | |
| SCHEMBL10242977 | 0.78 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HPGDSSMN1; SMN2 | |
| SCHEMBL9011202 | 0.77 | EPHX2 (0.67) | ALDH1A1SMN1; SMN2MEN1KMT2ACYP3A4 | |
| SCHEMBL24392693 | 0.77 | HPGDS (0.70) | HDAC3HDAC1HDAC2HPGDSSMN1; SMN2 | |
| SCHEMBL5020897 | 0.77 | HDAC3 (0.61) | HDAC3HDAC1HDAC2SMN1; SMN2DRD2 | |
| Iodide SCHEMBL9011381 | 0.76 | HSP90AA1 (0.49) | STAMBPHSP90AA1KDM4EALDH1A1HPGD | |
| SCHEMBL2639346 | 0.75 | MGAM (0.56) | HDAC3HDAC1HDAC2HPGDSDRD2 | |
| SCHEMBL29222038 | 0.75 | HDAC3 (0.61) | HDAC3HDAC1HDAC2HPGDSDRD2 | |
| SCHEMBL2639342 | 0.75 | PPARD (0.57) | HDAC3HDAC1HDAC2HPGDSDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5525727-A | ANALGESIC OR NARCOTIC ANTAGONIST | UNIVERSITY OF FLORIDA (US) | 1996-06-11 | — | — | US | disclosed |
| US-5187158-A | Sustained delivery of viricides | UNIVERSITY OF FLORIDA (US) | 1993-02-16 | — | — | US | disclosed |
| US-5008257-A | Penicillin or cephalosporin antibiotics | UNIVERSITY OF FLORIDA (US) | 1991-04-16 | — | — | US | disclosed |
| US-4900837-A | Brain-specific drug delivery of steroid sex hormones cleaved from pyridinium carboxylates and dihydro-pyridine carboxylate precursors | UNIVERSITY OF FLORIDA (US) | 1990-02-13 | — | — | US | disclosed |
| US-4880921-A | Brain-specific drug delivery | UNIVERSITY OF FLORIDA (US) | 1989-11-14 | — | — | US | disclosed |
| US-4824850-A | DIHYDROPYRIDINE-PYRIDINIUM SALT REDOX CARRIER | UNIVERSITY OF FLORIDA (US) | 1989-04-25 | — | — | US | disclosed |