Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A2 | P23975 | 2/20 | 0.44 |
| ▸ | HTR2A | P28223 | 1/20 | 0.44 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.44 |
| ▸ | HTR2B | P41595 | 1/20 | 0.44 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.44 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | NNMT | P40261 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 1/20 | 0.40 |
| ▸ | CPB2 | Q96IY4 | 1/20 | 0.38 |
| ▸ | APP | P05067 | 3/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12867094 | 0.85 | HCAR3 (0.42) | NNMTHCAR3CPB2APPCYP11B1 | |
| SCHEMBL22388076 | 0.81 | HCAR3 (0.39) | NNMTHCAR3CPB2CYP11B1CYP11B2 | |
| SCHEMBL18270406 | 0.81 | CPB2 (0.40) | NNMTHCAR3CPB2APPCYP11B1 | |
| Hydrochloric Acid SCHEMBL28410712 | 0.79 | HCAR3 (0.40) | SLC6A2SLC6A4SLC6A3NNMTHCAR3 | |
| SCHEMBL479854 | 0.77 | NNMT (0.47) | NNMTHCAR3CPB2APPCYP11B1 | |
| SCHEMBL22255185 | 0.76 | HCAR3 (0.41) | SLC6A2SLC6A4SLC6A3NNMTHCAR3 | |
| SCHEMBL12020150 | 0.75 | HCAR3 (0.46) | NNMTHCAR3CPB2APPCYP11B1 | |
| SCHEMBL5040778 | 0.74 | ALDH1A1 (0.57) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL23073868 | 0.74 | NR3C2 (0.44) | SLC6A2HTR2ASLC6A4HRH1HTR2B | |
| SCHEMBL22254985 | 0.74 | HCAR3 (0.39) | NNMTHCAR3CPB2APPCYP11B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180155340-A1 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | PRINCIPIA BIOPHARMA INC. | 2018-06-07 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180155340-A1 | QUINOLONE DERIVATIVES AS FGFR INHIBITORS | FGFR1, FGFR3, FGFR2 | SLC6A2 4363/4885HTR2A 4295/4885SLC6A4 4427/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.