SCHEMBL20230477

SCHEMBL20230477

c1ccc(-c2nc3c(-n4c5ccccc5c5ccccc54)nnc(-n4c5ccccc5c5ccccc54)c3nc2-c2ccccc2)cc1

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
KDM4E B2RXH2 3/20 0.42
L3MBTL1 Q9Y468 2/20 0.42
ATM Q13315 1/20 0.42
NPSR1 Q6W5P4 6/20 0.41
KMT2A Q03164 5/20 0.41
HTT P42858 4/20 0.41
MAPT P10636 2/20 0.41
MAPK1 P28482 1/20 0.41
MEN1 O00255 4/20 0.40
DHFR P00374 1/20 0.40
PIK3CG P48736 1/20 0.40
LMNA P02545 2/20 0.39
POLB P06746 1/20 0.39
HSD17B10 Q99714 1/20 0.39
SMO Q99835 2/20 0.38
ADORA2A P29274 1/20 0.38
ADORA1 P30542 1/20 0.38
GAA P10253 1/20 0.38
TDP1 Q9NUW8 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20230480 0.89 KDM4E (0.41) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL20230487 0.82 KDM4E (0.36) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL20230536 0.81 KDM4E (0.44) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL12014912 0.79 ADK (0.44) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL28471584 0.78 ALDH1A1 (0.42) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL12268646 0.77 L3MBTL1 (0.53) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL19655415 0.76 KDM4E (0.37) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL20230495 0.76 KDM4E (0.44) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL24036838 0.76 HSD17B10 (0.50) ALDH1A1KDM4EL3MBTL1ATMNPSR1
SCHEMBL20230482 0.76 PDE10A (0.37) ALDH1A1KDM4EL3MBTL1ATMNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-10388887-B2 Delayed fluorescence compound for organic EL device and using the same LUMINESCENCE TECHNOLOGY CORP. (TW) 2019-08-20 US disclosed
US-20180159049-A1 DELAYED FLUORESCENCE COMPOUND FOR ORGANIC EL DEVICE AND USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2018-06-07 US disclosed
US-20180159049-A1 DELAYED FLUORESCENCE COMPOUND FOR ORGANIC EL DEVICE AND USING THE SAME LUMINESCENCE TECHNOLOGY CORPORATION (TW) 2018-06-07 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-10388887-B2 Delayed fluorescence compound for organic EL device and using the same SLCO4C1, SLCO1A2, SLCO1B1 ALDH1A1 1664/4885KDM4E 1233/4885L3MBTL1 232/4885
US-20180159049-A1 DELAYED FLUORESCENCE COMPOUND FOR ORGANIC EL DEVICE AND USING THE SAME SLCO4C1, SLCO1A2, SLCO1B1 ALDH1A1 1664/4885KDM4E 1233/4885L3MBTL1 232/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.