Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRC | P12931 | 1/20 | 0.63 |
| ▸ | RAB9A | P51151 | 7/20 | 0.61 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.58 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.58 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.58 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.58 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.58 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.58 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.58 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.58 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.58 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.57 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6326069 | 0.94 | SRC (0.58) | SRCRAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL4113855 | 0.86 | RAB9A (0.79) | SRCRAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL9613184 | 0.85 | SRC (0.58) | SRCRAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL2022898 | 0.85 | POLB (0.57) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL155297 | 0.84 | RAB9A (0.64) | SRCRAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL5933551 | 0.84 | SRC (0.61) | SRCRAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL9312728 | 0.84 | HDAC3 (0.66) | SRCRAB9AHDAC3HDAC4HDAC1 | |
| SCHEMBL29092627 | 0.84 | POLB (0.50) | RAB9AHDAC3HDAC4HDAC1HDAC7 | |
| SCHEMBL2762349 | 0.84 | POLB (0.62) | SRCRAB9ANPC1KMT2AALDH1A1 | |
| SCHEMBL2019464 | 0.84 | POLB (0.70) | RAB9ANPC1KMT2AALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3536683-B1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | ASAHI CHEMICAL IND (JP) | 2021-11-24 | — | — | EP | disclosed |
| EP-3372579-B1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | ASAHI CHEMICAL IND (JP) | 2020-10-28 | — | — | EP | disclosed |
| EP-3536683-A1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2019-09-11 | — | — | EP | disclosed |
| US-10301417-B2 | Polyisocyanate composition and isocyanate polymer composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2019-05-28 | — | — | US | disclosed |
| US-10125212-B2 | Polyisocyanate composition and isocyanate polymer composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2018-11-13 | — | — | US | disclosed |
| EP-3372579-A1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | Asahi Kasei Kabushiki Kaisha (JP) | 2018-09-12 | — | — | EP | disclosed |
| US-20170298169-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2017-10-19 | — | — | US | disclosed |
| EP-2593078-B1 | CYCLOHEXYL CARBAMATE COMPOUNDS AS ACTIVE ANTI-CELLULITE INGREDIENTS | SYMRISE AG (DE) | 2016-11-30 | — | — | EP | disclosed |
| US-9145358-B2 | N-substituted carbamic acid ester production method, isocyanate production method using such N-substituted carbamic acid ester, and composition for transfer and storage of N-substituted carbamic acid ester comprising N-substituted carbamic acid ester and aromatic hydroxy compound | ASAHI KASEI CHEMICALS CORPORATION (JP) | 2015-09-29 | — | — | US | disclosed |
| EP-2915803-A1 | POLYISOCYANATE COMPOSITION AND ISOCYANATE POLYMER COMPOSITION | Asahi Kasei Chemicals Corporation (JP) | 2015-09-09 | — | — | EP | disclosed |
| EP-0111955-A1 | Prostaglandin intermediates | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-06-27 | — | — | EP | disclosed |
| US-4438136-A | INHIBITION OF THROMBOXANE ACTIVITY | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1984-03-20 | — | — | US | disclosed |
| EP-0013608-B1 | SUBSTITUTED BICYCLO (2,2,1)HEPTANES AND HEPT-2-ENES AND THEIR PHARMACEUTICAL COMPOSITIONS | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1983-06-15 | — | — | EP | disclosed |
| US-4369141-A | Process to improve isocyanate yield upon pyrolysis of a polyfunctional urethane which has been extracted with a combination of hydrochloric acid and alcohol | ATLANTIC RICHFIELD COMPANY (US) | 1983-01-18 | — | — | US | disclosed |
| EP-0043292-A2 | Prostaglandins | NATIONAL RESEARCH DEVELOPMENT CORPORATION (GB) | 1982-01-06 | — | — | EP | disclosed |
| US-4292254-A | COSOLVENT, SOLVENT EXTRACTION, AQUEOUS ACID | ATLANTIC RICHFIELD COMPANY (US) | 1981-09-29 | — | — | US | disclosed |
| US-4290968-A | REMOVAL OF AMINE BY-PRODUCTS WITH ION EXCHANGE RESINS | ATLANTIC RICHFIELD COMPANY (US) | 1981-09-22 | — | — | US | disclosed |
| US-4267353-A | Preparation of aromatic urethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1981-05-12 | — | — | US | disclosed |
| US-4236016-A | Process for the preparation of urethanes | BAYER AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| WO-1980001382-A1 | SUBSTITUTED (2,2,1) HEPTANES AND HEPT-2-ENES AND THEIR PHARMACEUTICAL COMPOSITIONS AS INHIBITORS OF THROMBOXANE ACTIVITY | JONES R (GB) | 1980-07-10 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10301417-B2 | Polyisocyanate composition and isocyanate polymer composition | PAH, ALKBH1, ALKBH3 | SRC 3223/4885RAB9A 4175/4885HDAC3 253/4885 |
| US-20170298169-A1 | Polyisocyanate Composition and Isocyanate Polymer Composition | TST, SUDS3, SCLY | SRC 1581/4885RAB9A 4633/4885HDAC3 48/4885 |
| US-10125212-B2 | Polyisocyanate composition and isocyanate polymer composition | TST, SUDS3, SCLY | SRC 1581/4885RAB9A 4633/4885HDAC3 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.