Known targets — ChEMBL curated mechanism
ACHECHRM1CHRM3CHRNA1CHRNB1CHRNDCHRNECHRNG
The experimentally established mechanism targets of Iodide. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TERT | O14746 | 6/20 | 0.67 |
| ▸ | STAT3 | P40763 | 1/20 | 0.65 |
| ▸ | STAT1 | P42224 | 1/20 | 0.65 |
| ▸ | TOP1 | P11387 | 4/20 | 0.38 |
| ▸ | CYCS | P99999 | 3/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 1/20 | 0.37 |
| ▸ | ABCG2 | Q9UNQ0 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Iodide SCHEMBL30767160 | 1.00 | TERT (0.67) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL3465842 | 0.91 | TERT (0.65) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL30293296 | 0.86 | STAT3 (0.86) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL31550992 | 0.86 | STAT3 (0.86) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL1224432 | 0.86 | STAT3 (0.86) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL31324940 | 0.85 | STAT3 (0.84) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL17841775 | 0.85 | STAT3 (0.84) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL31324939 | 0.85 | STAT3 (0.84) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL24270402 | 0.84 | STAT3 (0.82) | TERTSTAT3STAT1TOP1CYCS | |
| SCHEMBL869153 | 0.83 | TERT (0.94) | TERTSTAT3STAT1TOP1CYCS |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110730782-B | Photodynamic therapy compounds and photodynamic therapy methods | 光盐生物科技有限公司 | 2024-01-02 | — | — | CN | disclosed |
| US-11147797-B2 | Photodynamic therapeutic compounds and photodynamic methods of treatment | SALT AND LIGHT PHARMACEUTICALS PTY. LTD. (AU) | 2021-10-19 | — | — | US | disclosed |
| US-20190307725-A1 | PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT | SALT AND LIGHT PHARMACEUTICALS PTY. LTD. (AU) | 2019-10-10 | — | — | US | disclosed |
| EP-3548494-A1 | PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT | Salt and Light Pharmaceuticals Pty. Ltd. (AU) | 2019-10-09 | — | — | EP | disclosed |
| WO-2018102849-A1 | PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT | SALT AND LIGHT PHARMACEUTICALS PTY. LTD. (AU) | 2018-06-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190307725-A1 | PHOTODYNAMIC THERAPEUTIC COMPOUNDS AND PHOTODYNAMIC METHODS OF TREATMENT | PPOX, QDPR, ALDH1A2 | TERT 1213/4885STAT3 115/4885STAT1 270/4885 |
| US-11147797-B2 | Photodynamic therapeutic compounds and photodynamic methods of treatment | PPOX, QDPR, ALDH1A2 | TERT 1213/4885STAT3 115/4885STAT1 270/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.