Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR1A | P08908 | 1/20 | 0.35 |
| ▸ | GJB2 | P29033 | 2/20 | 0.34 |
| ▸ | NT5E | P21589 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TACR2 | P21452 | 3/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 3/20 | 0.32 |
| ▸ | CDC25B | P30305 | 2/20 | 0.32 |
| ▸ | SSTR4 | P31391 | 3/20 | 0.32 |
| ▸ | SSTR1 | P30872 | 1/20 | 0.32 |
| ▸ | SSTR2 | P30874 | 1/20 | 0.32 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.32 |
| ▸ | SSTR5 | P35346 | 1/20 | 0.32 |
| ▸ | BCHE | P06276 | 2/20 | 0.31 |
| ▸ | ACHE | P22303 | 2/20 | 0.31 |
| ▸ | PTPN2 | P17706 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18412648 | 1.00 | HTR1A (0.35) | HTR1AGJB2NT5EALDH1A1TACR2 | |
| SCHEMBL22013739 | 0.88 | GJB2 (0.35) | HTR1AGJB2NT5EPTPN1CDC25B | |
| SCHEMBL22991832 | 0.88 | GJB2 (0.35) | HTR1AGJB2NT5EPTPN1CDC25B | |
| SCHEMBL18394265 | 0.88 | GJB2 (0.35) | HTR1AGJB2NT5EPTPN1CDC25B | |
| SCHEMBL22842844 | 0.81 | SSTR1 (0.39) | HTR1AGJB2NT5EPTPN1CDC25B | |
| SCHEMBL25964180 | 0.81 | SSTR1 (0.39) | HTR1AGJB2NT5EPTPN1CDC25B | |
| SCHEMBL21749230 | 0.78 | ALDH1A1 (0.39) | HTR1AGJB2NT5EALDH1A1TACR2 | |
| SCHEMBL21756600 | 0.78 | ALDH1A1 (0.39) | HTR1AGJB2NT5EALDH1A1TACR2 | |
| SCHEMBL25964302 | 0.77 | SSTR1 (0.41) | GJB2NT5EPTPN1CDC25BSSTR4 | |
| SCHEMBL25964134 | 0.75 | SSTR1 (0.39) | HTR1AGJB2NT5EPTPN1CDC25B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9994605-B2 | Carbohydrate ligands that bind to IgM antibodies against myelin-associated glycoprotein | UNIVERSITAET BASEL (CH) | 2018-06-12 | — | — | US | disclosed |