Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC9A1 | P19634 | 8/20 | 0.54 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.54 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | BRD4 | O60885 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24051506 | 0.80 | SLC9A1 (0.68) | SLC9A1GRM2TDP1KCNMA1 | |
| SCHEMBL22000732 | 0.75 | GRM2 (0.75) | SLC9A1GRM2TDP1KCNMA1LMNA | |
| SCHEMBL20815428 | 0.73 | KCNMA1 (0.64) | SLC9A1GRM2TDP1KCNMA1ALDH1A1 | |
| SCHEMBL7599503 | 0.71 | SLC9A1 (0.69) | SLC9A1GRM2TDP1ALDH1A1LMNA | |
| SCHEMBL23299012 | 0.71 | KCNMA1 (0.54) | SLC9A1GRM2TDP1KCNMA1ALDH1A1 | |
| SCHEMBL29839046 | 0.71 | KCNMA1 (0.69) | SLC9A1GRM2TDP1KCNMA1ALDH1A1 | |
| SCHEMBL27787690 | 0.71 | KCNMA1 (0.60) | SLC9A1GRM2TDP1KCNMA1ATM | |
| SCHEMBL23058946 | 0.71 | KCNMA1 (0.50) | SLC9A1GRM2TDP1KCNMA1ALDH1A1 | |
| SCHEMBL2734889 | 0.71 | GRM2 (1.00) | SLC9A1GRM2TDP1KCNMA1ALDH1A1 | |
| SCHEMBL45852 | 0.70 | SLC9A1 (1.00) | SLC9A1GRM2TDP1KCNMA1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3067350-B1 | METALLOENZYME INHIBITOR COMPOUNDS | VIAMET PHARMACEUTICALS NC INC (US) | 2018-06-13 | — | — | EP | disclosed |