Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | CCR3 | P51677 | 3/20 | 0.45 |
| ▸ | ACHE | P22303 | 2/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.42 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CARM1 | Q86X55 | 1/20 | 0.40 |
| ▸ | PRMT6 | Q96LA8 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MC4R | P32245 | 3/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16333179 | 0.83 | CYP1A2 (0.57) | CCR3TAAR1TSHRCYP1A2CYP3A4 | |
| SCHEMBL7727307 | 0.83 | CYP1A2 (0.57) | CCR3TAAR1TSHRCYP1A2CYP3A4 | |
| SCHEMBL6478479 | 0.83 | CYP1A2 (0.57) | CCR3TAAR1TSHRCYP1A2CYP3A4 | |
| SCHEMBL8784254 | 0.81 | L3MBTL3 (0.58) | CCR3TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL8276876 | 0.79 | ALDH1A1 (0.49) | CCR3CYP3A4CYP2C19ALDH1A1 | |
| SCHEMBL17179705 | 0.79 | GAA (0.60) | ALDH1A1 | |
| SCHEMBL4070780 | 0.75 | HRH3 (0.50) | CCR3TSHRCYP1A2CYP3A4CYP2D6 | |
| SCHEMBL3457922 | 0.74 | L3MBTL3 (0.61) | SIGMAR1TSHRCYP2D6CYP2C19MEN1 | |
| SCHEMBL12859443 | 0.73 | CYP2D6 (0.70) | SIGMAR1ACHEHSP90AA1TSHRCYP2D6 | |
| SCHEMBL9390717 | 0.72 | MCHR1 (0.40) | CCR3TAAR1TSHRCYP2D6MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2892525-B1 | METHODS OF TREATING MUSCULAR DYSTROPHY | UNIV NEVADA RENO (US) | 2018-06-13 | — | — | EP | disclosed |