SCHEMBL536167

SCHEMBL536167

CC(=O)OC(C)(C)c1cccc(C(C)(C)OC(C)=O)c1C(C)(C)OC(C)=O

nearest known ligand 0.36

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 1/20 0.36
CA2 P00918 1/20 0.35
CYP2C19 P33261 2/20 0.34
TSHR P16473 2/20 0.34
CYP2D6 P10635 1/20 0.34
CYP2C9 P11712 1/20 0.34
GAA P10253 1/20 0.33
LMNA P02545 1/20 0.32
GABRA1 P14867 1/20 0.31
GABRB2 P47870 1/20 0.31
ALDH1A1 P00352 3/20 0.31
HIF1A Q16665 1/20 0.31
TDP1 Q9NUW8 2/20 0.30
THRB P10828 1/20 0.30
NPSR1 Q6W5P4 1/20 0.30
ATM Q13315 1/20 0.30
MAPK1 P28482 1/20 0.30
KDM4E B2RXH2 1/20 0.30
HPGD P15428 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9466322 0.94 CA2 (0.41) CYP3A4CA2CYP2C19TSHRCYP2D6
SCHEMBL3367791 0.90 CA2 (0.39) CYP3A4CA2CYP2C19TSHRCYP2D6
SCHEMBL5656237 0.85 ALDH1A1 (0.38) CYP3A4CA2CYP2C19TSHRCYP2D6
SCHEMBL9465937 0.84 BACE1 (0.39) CYP2C19CYP2C9ALDH1A1
SCHEMBL536687 0.79 ACHE (0.35) CA2CYP2C19CYP2D6GABRA1GABRB2
SCHEMBL22642594 0.78 GABRA1 (0.38) CYP2C19TSHRCYP2D6CYP2C9GAA
SCHEMBL26059408 0.78 TSHR (0.52) CYP3A4CA2CYP2C19TSHRCYP2D6
SCHEMBL16124322 0.78 ALDH1A1 (0.45) CYP2C19CYP2C9GAAALDH1A1MAPK1
SCHEMBL25563999 0.78 CES2 (0.44) CYP3A4CA2HPGD
Ammonia Solution, Strong SCHEMBL1742567 0.77 ALDH1A1 (0.39) CYP3A4CA2CYP2C19TSHRCYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2925804-B1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES CHEVRON ORONITE CO (US) 2019-02-20 EP disclosed
EP-2414432-B1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION CHEVRON ORONITE CO (US) 2017-05-31 EP disclosed
US-9315595-B2 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation CHEVRON ORONITE COMPANY LLC (US) 2016-04-19 US disclosed
US-9243203-B2 Copolymers of polyaminopolyolefins and polyanhydrides and methods of their preparation CHEVRON ORONITE COMPANY LLC (US) 2016-01-26 US disclosed
EP-2925804-A1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES Chevron Oronite Company LLC (US) 2015-10-07 EP disclosed
US-20140155308-A1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES AND METHODS OF THEIR PREPARATION CHEVRON ORONITE COMPANY LLC (US) 2014-06-05 US disclosed
WO-2014085047-A1 COPOLYMERS OF POLYAMINOPOLYOLEFINS AND POLYANHYDRIDES CHEVRON ORONITE COMPANY LLC (US) 2014-06-05 WO disclosed
US-20140031497-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2014-01-30 US disclosed
US-8552122-B2 Amine-terminated telechelic polymers and precursors thereto and methods for their preparation THE UNIVERSITY OF SOUTHERN MISSISSIPPI (US) 2013-10-08 US disclosed
EP-2414432-A2 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION Chevron Oronite Company LLC (US) 2012-02-08 EP disclosed
WO-2010117619-A2 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION CHEVRON ORONITE COMPANY LLC (US) 2010-10-14 WO disclosed
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION UNIVERSITY OF SOUTHERN MISSISSIPPI 2010-09-30 US disclosed
US-5248746-A Cationic polymerization, molecular weight control NIPPON ZEON CO., LTD. (JP) 1993-09-28 US disclosed
EP-0451679-A2 Method of producing polymers NIPPON ZEON CO., LTD. (JP) 1991-10-16 EP disclosed
EP-0397081-A2 Process for preparation of polymer NIPPON ZEON CO., LTD. (JP) 1990-11-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100249001-A1 AMINE-TERMINATED TELECHELIC POLYMERS AND PRECURSORS THERETO AND METHODS FOR THEIR PREPARATION TERT, TELO2, TSPO CYP3A4 3556/4885CA2 3021/4885CYP2C19 4189/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.