Sugi Predict

Sugi Predict / Compounds / SCHEMBL2024740

SCHEMBL2024740

SCHEMBL2024740

O=C1C2C3C=CC(O3)C2C(=O)N1CCOCCO

nearest known ligand 0.43

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ ALDH1A1 P00352 10/20 0.43
▸ PKM P14618 2/20 0.40
▸ TDP1 Q9NUW8 2/20 0.40
▸ POLB P06746 1/20 0.40
▸ CTDSP1 Q9GZU7 1/20 0.40
▸ HTT P42858 2/20 0.40
▸ HSD17B10 Q99714 2/20 0.40
▸ USP2 O75604 1/20 0.40
▸ TSHR P16473 1/20 0.40
▸ ATM Q13315 2/20 0.38
▸ MAPT P10636 3/20 0.38
▸ MGLL Q99685 1/20 0.37
▸ HPGD P15428 1/20 0.37
▸ CACNA1B Q00975 1/20 0.37
▸ APBA1 Q02410 1/20 0.37
▸ OPRM1 P35372 1/20 0.35
▸ OPRD1 P41143 1/20 0.35
▸ OPRK1 P41145 1/20 0.35
▸ NPC1 O15118 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL18126828 1.00 ALDH1A1 (0.43) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL12284562 1.00 ALDH1A1 (0.43) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL12286843 0.98 ALDH1A1 (0.43) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL10126651 0.98 ALDH1A1 (0.43) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL14129235 0.98 ALDH1A1 (0.43) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL2756797 0.92 ALDH1A1 (0.45) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL15851407 0.84 ALDH1A1 (0.40) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL15851403 0.84 ALDH1A1 (0.40) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL20725008 0.84 ALDH1A1 (0.40) ALDH1A1PKMTDP1POLBCTDSP1
SCHEMBL239348 0.83 ALDH1A1 (0.50) ALDH1A1PKMHTTHSD17B10USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240293585-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS KODIAK SCIENCES INC. 2024-09-05 — — US disclosed
US-20240197810-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC. 2024-06-20 — — US disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 — — US disclosed
US-20230381323-A1 RELEASABLE CONJUGATES FISH & RICHARDSON PC 2023-11-30 — — US disclosed
US-11819531-B2 Multifunctional zwitterionic polymer conjugates KODIAK SCIENCES INC. (US) 2023-11-21 — — US disclosed
EP-3659591-B1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2023-10-25 — — EP disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 — — US disclosed
US-11786599-B2 Releasable conjugates QUIAPEG PHARMACEUTICALS AB (SE) 2023-10-17 — — US disclosed
US-20230277616-A9 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC. 2023-09-07 — — US disclosed
EP-4029510-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS Kodiak Sciences Inc. (US) 2022-07-20 — — EP disclosed
US-20170008998-A1 Shape-Memory-Self-Healing Polymers (SMSHPS) UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. 2017-01-12 — — US disclosed
US-20160287715-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES KODIAK SCIENCES INC (US) 2016-10-06 — — US disclosed
US-20140024776-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS OLIGASIS (US) 2014-01-23 — — US disclosed
US-20130045522-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2013-02-21 — — US disclosed
EP-2558538-A2 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS Oligasis (US) 2013-02-20 — — EP disclosed
US-8324358-B2 Polymer compositions and uses thereof MCGILL UNIVERSITY (CA) 2012-12-04 — — US disclosed
EP-2512462-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES Oligasis (US) 2012-10-24 — — EP disclosed
WO-2011130694-A2 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS OLIGASIS (US) 2011-10-20 — — WO disclosed
WO-2011075736-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES OLIGASIS (US) 2011-06-23 — — WO disclosed
US-20090130665-A1 POLYMER COMPOSITIONS AND USES THEREOF MCGILL UNIVERSITY (CA) 2009-05-21 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (8 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240293585-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS ACP1, PHOSPHO1, PARG ALDH1A1 4348/4885PKM 2828/4885TDP1 3781/4885
US-20230277616-A9 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 ALDH1A1 4195/4885PKM 3803/4885TDP1 3072/4885
US-20160287715-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 ALDH1A1 4195/4885PKM 3803/4885TDP1 3072/4885
US-20140024776-A1 HIGH MOLECULAR WEIGHT ZWITTERION-CONTAINING POLYMERS ACP1, PHOSPHO1, PARG ALDH1A1 4348/4885PKM 2828/4885TDP1 3781/4885
US-20230381323-A1 RELEASABLE CONJUGATES GUSB, ABCB11, UGT2B7 ALDH1A1 72/4885PKM 2753/4885TDP1 1238/4885
US-20240197810-A1 MULTIFUNCTIONAL ZWITTERIONIC POLYMER CONJUGATES PHOSPHO1, MSN, ZW10 ALDH1A1 4195/4885PKM 3803/4885TDP1 3072/4885
US-11819531-B2 Multifunctional zwitterionic polymer conjugates PHOSPHO1, MSN, ZW10 ALDH1A1 4195/4885PKM 3803/4885TDP1 3072/4885
US-11786599-B2 Releasable conjugates GUSB, ABCB11, UGT2B7 ALDH1A1 72/4885PKM 2753/4885TDP1 1238/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.