Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | RXRA | P19793 | 2/20 | 0.41 |
| ▸ | RXRB | P28702 | 2/20 | 0.41 |
| ▸ | RXRG | P48443 | 1/20 | 0.40 |
| ▸ | HSD17B1 | P14061 | 3/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
| ▸ | HSD17B2 | P37059 | 2/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.32 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | BRD9 | Q9H8M2 | 1/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26032094 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308729 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308756 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308731 | 0.89 | ALDH1A1 (0.37) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308750 | 0.87 | ALDH1A1 (0.35) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308808 | 0.85 | HSD17B1 (0.38) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308806 | 0.84 | RXRA (0.36) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308775 | 0.82 | HSD17B1 (0.40) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308776 | 0.81 | RXRA (0.35) | ALDH1A1CYP3A4TSHRTDP1RXRA | |
| SCHEMBL18308809 | 0.81 | HSD17B1 (0.35) | ALDH1A1CYP3A4TSHRTDP1RXRA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180163137-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | MERCK PATENT GMBH (DE) | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180163137-A1 | POLYMERISABLE COMPOUNDS AND THE USE THEREOF IN LIQUID-CRYSTAL DISPLAYS | VCL, ILK, LCP1 | ALDH1A1 4650/4885CYP3A4 1701/4885TSHR 4834/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.