Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A12 | P48065 | 5/20 | 0.48 |
| ▸ | SLC6A11 | P48066 | 5/20 | 0.48 |
| ▸ | SLC6A13 | Q9NSD5 | 5/20 | 0.48 |
| ▸ | SLC6A1 | P30531 | 2/20 | 0.47 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.47 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.47 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.47 |
| ▸ | GABRR1 | P24046 | 1/20 | 0.47 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.47 |
| ▸ | ANPEP | P15144 | 1/20 | 0.44 |
| ▸ | ENPEP | Q07075 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | ADCY5 | O95622 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.35 |
| ▸ | PLAT | P00750 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13834830 | 1.00 | SLC6A12 (0.48) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL15514904 | 1.00 | SLC6A12 (0.48) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL29955739 | 1.00 | SLC6A12 (0.48) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL29956796 | 1.00 | SLC6A12 (0.48) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| Hydrochloric Acid SCHEMBL26087240 | 0.98 | SLC6A12 (0.50) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| Hydrochloric Acid SCHEMBL26086954 | 0.98 | SLC6A12 (0.50) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL7490859 | 0.87 | SLC6A12 (0.45) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL7490854 | 0.87 | SLC6A12 (0.45) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL7040010 | 0.87 | SLC6A12 (0.45) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 | |
| SCHEMBL229034 | 0.86 | ANPEP (0.52) | SLC6A12SLC6A11SLC6A13SLC6A1GABRA5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| US-20180161349-A1 | ARGINASE INHIBITOR COMBINATION THERAPIES | PRECISION PHARMACEUTICALS, INC. | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180161349-A1 | ARGINASE INHIBITOR COMBINATION THERAPIES | ARG1, ARG2, PRMT3 | SLC6A12 4295/4885SLC6A11 4375/4885SLC6A13 4106/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.