Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 7/20 | 0.65 |
| ▸ | GSTP1 | P09211 | 1/20 | 0.59 |
| ▸ | GAA | P10253 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | MAOA | P21397 | 1/20 | 0.58 |
| ▸ | RAB9A | P51151 | 1/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.58 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.56 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL566543 | 0.91 | MAOB (0.71) | MAOBGAAMAPTMAOARAB9A | |
| Hydrochloric Acid SCHEMBL4449735 | 0.89 | MAOB (0.73) | MAOBGAAMAPTMAOARAB9A | |
| SCHEMBL7349864 | 0.86 | MAOB (0.64) | FFAR1MAOBGSTP1LTA4HPLA2G2A | |
| SCHEMBL20240299 | 0.86 | MAOB (0.79) | FFAR1MAOBGSTP1GAAMAPT | |
| Hydrochloric Acid SCHEMBL2568656 | 0.85 | MAOB (0.65) | FFAR1MAOBGSTP1LTA4HPLA2G2A | |
| SCHEMBL23483029 | 0.83 | LMNA (0.69) | FFAR1MAOBGSTP1GAAMAPT | |
| SCHEMBL12285274 | 0.83 | GSTP1 (0.68) | FFAR1MAOBGSTP1GAAMAPT | |
| SCHEMBL23665904 | 0.83 | GSTP1 (0.68) | FFAR1MAOBGSTP1GAAMAPT | |
| SCHEMBL1096817 | 0.83 | LMNA (0.69) | FFAR1MAOBGSTP1GAAMAPT | |
| SCHEMBL172790 | 0.83 | TAAR1 (0.71) | MAOBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10385007-B2 | Monamine and monoamine derivatives as inhibitors of leukotriene A4 hydrolase | CELTAXSYS, INC. (US) | 2019-08-20 | — | — | US | disclosed |
| WO-2018107158-A1 | MONAMINE AND MONOAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | CELTAXSYS, INC. (US) | 2018-06-14 | — | — | WO | disclosed |
| US-20180162802-A1 | MONAMINE AND MONOAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | CELLTAXIS, LLC | 2018-06-14 | — | — | US | disclosed |
| US-20180162802-A1 | MONAMINE AND MONOAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | CELLTAXIS, LLC | 2018-06-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10385007-B2 | Monamine and monoamine derivatives as inhibitors of leukotriene A4 hydrolase | LTA4H, MAOB, LTB4R | FFAR1 504/4885MAOB 2/4885GSTP1 2718/4885 |
| US-20180162802-A1 | MONAMINE AND MONOAMINE DERIVATIVES AS INHIBITORS OF LEUKOTRIENE A4 HYDROLASE | LTA4H, MAOB, LTB4R | FFAR1 504/4885MAOB 2/4885GSTP1 2718/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.