SCHEMBL202552

SCHEMBL202552

CC1(COC(=O)c2ccccc2-c2ccccc2)CC2C=CC1C2

nearest known ligand 0.44

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
SCN1A P35498 5/20 0.44
SCN2A Q99250 5/20 0.44
SCN3A Q9NY46 5/20 0.44
CHRNB2 P17787 9/20 0.43
CHRNA4 P43681 9/20 0.43
CHRNB4 P30926 7/20 0.43
CHRNA3 P32297 7/20 0.43
LMNA P02545 1/20 0.40
CNR2 P34972 1/20 0.35
TSHR P16473 1/20 0.35
MEN1 O00255 1/20 0.35
KMT2A Q03164 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
SLC6A4 P31645 1/20 0.35
SLC6A3 Q01959 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200205 0.84 KDM4E (0.43) SCN1ASCN2ASCN3AMEN1KMT2A
SCHEMBL202759 0.82 CDC25B (0.46) CNR2KMT2A
SCHEMBL2892928 0.80 SCN1A (0.50) SCN1ASCN2ASCN3ACHRNB2CHRNA4
SCHEMBL200989 0.75 HRH3 (0.44) MEN1KMT2ASMN1; SMN2
SCHEMBL13025197 0.73 CYP2D6 (0.36) SMN1; SMN2
SCHEMBL396552 0.71 TSHR (0.69) SCN1ASCN2ASCN3ACHRNB2CHRNA4
SCHEMBL5355018 0.71 CYP2D6 (0.35) SMN1; SMN2
Bicarbonate SCHEMBL27449726 0.70 TSHR (0.67) SCN1ASCN2ASCN3ACHRNB2CHRNA4
SCHEMBL25049835 0.70 GAA (0.44) LMNAMEN1KMT2ASMN1; SMN2
SCHEMBL201988 0.69 CHRNB2 (0.56) SCN1ASCN2ASCN3ACHRNB2CHRNA4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006098162-A1 OPTICAL COMPENSATION SHEET, POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY FUJIFILM CORPORATION (JP) 2006-09-21 WO disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed