SCHEMBL202759

SCHEMBL202759

CC1(COC(=O)c2cccc3ccccc23)CC2C=CC1C2

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
CDC25B P30305 2/20 0.46
HRH3 Q9Y5N1 2/20 0.42
ALDH1A1 P00352 5/20 0.41
KDM4E B2RXH2 4/20 0.41
CDC25A P30304 1/20 0.41
CDC25C P30307 1/20 0.41
ADRB2 P07550 2/20 0.41
ADRB1 P08588 2/20 0.41
ADRB3 P13945 2/20 0.41
KMT2A Q03164 2/20 0.40
HPGD P15428 2/20 0.39
MAPT P10636 1/20 0.39
CACNA1B Q00975 2/20 0.39
APBA1 Q02410 2/20 0.39
DRD3 P35462 1/20 0.38
P2RX7 Q99572 1/20 0.38
POLB P06746 1/20 0.37
GAA P10253 1/20 0.37
CNR2 P34972 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL200490 0.84 KDM4E (0.39) ALDH1A1KDM4EKMT2AHPGDMAPT
SCHEMBL202552 0.82 SCN1A (0.44) KMT2ACNR2
SCHEMBL2899391 0.80 KMT2A (0.42) CDC25BHRH3ALDH1A1KDM4EADRB2
SCHEMBL200989 0.80 HRH3 (0.44) HRH3ALDH1A1KDM4EADRB2ADRB1
SCHEMBL200205 0.77 KDM4E (0.43) ALDH1A1KDM4EKMT2A
SCHEMBL277672 0.71 CDC25B (0.82) CDC25BHRH3ALDH1A1KDM4ECDC25A
SCHEMBL5355018 0.71 CYP2D6 (0.35) P2RX7
SCHEMBL18544158 0.71 PTPN1 (0.43) CDC25BALDH1A1KDM4EKMT2AHPGD
SCHEMBL5358484 0.70 ALDH1A1 (0.38) ALDH1A1
SCHEMBL203615 0.69 CDC25B (0.44) CDC25BHRH3ALDH1A1KDM4ECDC25A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-9417477-B2 Polarizing plate and liquid crystal display device FUJIFILM CORPORATION (JP) 2016-08-16 US disclosed
US-20150146140-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2015-05-28 US disclosed
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-7719644-B2 Optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2010-05-18 US disclosed
US-20090033835-A1 Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2009-02-05 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-20080143928-A1 Polarizing Plate and Liquid Crystal Display Device FUJIFILM CORPORATION (JP) 2008-06-19 US disclosed
WO-2006082818-A1 POLARIZING PLATE AND LIQUID CRYSTAL DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2006-08-10 WO disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed