SCHEMBL200989

SCHEMBL200989

CC1(COC(=O)c2ccc3ccccc3c2)CC2C=CC1C2

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HRH3 Q9Y5N1 2/20 0.44
DRD3 P35462 1/20 0.42
ADRB2 P07550 1/20 0.41
ADRB1 P08588 1/20 0.41
ADRB3 P13945 1/20 0.41
KDM4E B2RXH2 5/20 0.39
HPGD P15428 4/20 0.39
SMN1; SMN2 Q16637 2/20 0.39
PTPN1 P18031 1/20 0.38
MAPT P10636 5/20 0.38
ALDH1A1 P00352 3/20 0.37
NPC1 O15118 3/20 0.37
KMT2A Q03164 2/20 0.37
POLB P06746 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 2/20 0.37
NPSR1 Q6W5P4 1/20 0.37
MEN1 O00255 1/20 0.36
CES2 O00748 1/20 0.36
CES1 P23141 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4934163 0.89 HRH3 (0.47) HRH3DRD3ADRB2ADRB1ADRB3
SCHEMBL200205 0.84 KDM4E (0.43) KDM4ESMN1; SMN2ALDH1A1NPC1KMT2A
SCHEMBL200490 0.82 KDM4E (0.39) KDM4EHPGDMAPTALDH1A1KMT2A
SCHEMBL2899258 0.80 MAPT (0.40) HRH3DRD3ADRB2ADRB1ADRB3
SCHEMBL4934176 0.80 HRH3 (0.44) HRH3DRD3ADRB2ADRB1ADRB3
SCHEMBL202759 0.80 CDC25B (0.46) HRH3DRD3ADRB2ADRB1ADRB3
SCHEMBL202552 0.75 SCN1A (0.44) SMN1; SMN2KMT2AMEN1
SCHEMBL571295 0.71 CA12 (0.59) HRH3DRD3ADRB2ADRB1ADRB3
SCHEMBL30684671 0.71 CA12 (0.59) HRH3DRD3ADRB2ADRB1ADRB3
SCHEMBL5355018 0.71 CYP2D6 (0.35) SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8089593-B2 Optical resin film, optical compensation sheet, polarizing plate and liquid crystal display FUJIFILM CORPORATION (JP) 2012-01-03 US disclosed
US-20080284957-A1 Optical Resin Film, Optical Compensation Sheet, Polarizing Plate and Liquid Crystal Display FUJIFILM CORPORATION (JP) 2008-11-20 US disclosed
US-7008569-B2 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2006-03-07 US disclosed
US-20040057141-A1 Thermoplastic norbornene resin based optical film JSR CORPORATION (JP) 2004-03-25 US disclosed
EP-1395855-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR Corporation (JP) 2004-03-10 EP disclosed
WO-2002088784-A2 THERMOPLASTIC NORBORNENE RESIN BASED OPTICAL FILM JSR CORPORATION (JP) 2002-11-07 WO disclosed