SCHEMBL20258992

SCHEMBL20258992

O=C1c2ccccc2-c2nccc3c2c1cc1c(Cl)nccc13

nearest known ligand 0.54

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MAOA P21397 3/20 0.54
ALDH1A1 P00352 1/20 0.47
CTSL P07711 1/20 0.42
PTPRC P08575 1/20 0.42
CTSS P25774 1/20 0.42
PTPN13 Q12923 1/20 0.42
MAOB P27338 1/20 0.41
TOP2A P11388 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20259175 0.75 CYP1A1 (0.40) MAOAALDH1A1MAOB
SCHEMBL28756517 0.72 MAOA (0.62) MAOAALDH1A1CTSLPTPRCCTSS
SCHEMBL25322919 0.71 MAOA (0.65) MAOAMAOB
SCHEMBL7804497 0.71 MAOA (0.53) MAOAALDH1A1CTSLPTPRCCTSS
SCHEMBL20258993 0.70 TTR (0.35) MAOAALDH1A1
SCHEMBL12288848 0.70 MAOA (0.60) MAOAMAOB
SCHEMBL1969983 0.70 MAOA (1.00) MAOAALDH1A1CTSLPTPRCCTSS
SCHEMBL28075835 0.69 MAOA (0.97) MAOAALDH1A1CTSLPTPRCCTSS
SCHEMBL30416588 0.69 MAOA (0.97) MAOAALDH1A1CTSLPTPRCCTSS
Benzosampangine SCHEMBL29601408 0.68 TOP2A (0.79) MAOAALDH1A1CTSLPTPRCCTSS

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11466021-B2 Materials for organic electroluminescent devices MERCK PATENT GMBH (DE) 2022-10-11 US disclosed
EP-3548486-B1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2021-10-27 EP disclosed
US-20200199138-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2020-06-25 US disclosed
WO-2018104194-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES MERCK PATENT GMBH (DE) 2018-06-14 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200199138-A1 MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES OR10J3, L1CAM, EPCAM MAOA 343/4885ALDH1A1 441/4885CTSL 4146/4885
US-11466021-B2 Materials for organic electroluminescent devices OR10J3, L1CAM, EPCAM MAOA 343/4885ALDH1A1 441/4885CTSL 4146/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.