Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 2/20 | 1.00 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.58 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.58 |
| ▸ | CASP1 | P29466 | 1/20 | 0.58 |
| ▸ | CASP7 | P55210 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.53 |
| ▸ | CTSL | P07711 | 1/20 | 0.52 |
| ▸ | PTPRC | P08575 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 1/20 | 0.52 |
| ▸ | PTPN13 | Q12923 | 1/20 | 0.52 |
| ▸ | CES2 | O00748 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | CES1 | P23141 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28075835 | 0.98 | MAOA (0.97) | MAOACYP3A4PABPC1DNMT1CASP1 | |
| SCHEMBL30416588 | 0.98 | MAOA (0.97) | MAOACYP3A4PABPC1DNMT1CASP1 | |
| SCHEMBL25380689 | 0.86 | MAOA (0.75) | MAOACYP3A4PABPC1DNMT1CASP1 | |
| SCHEMBL29869412 | 0.86 | MAOA (0.75) | MAOACYP3A4PABPC1DNMT1CASP1 | |
| Sampangine SCHEMBL6230423 | 0.85 | MAOA (0.74) | MAOAALDH1A1CTSLPTPRCCTSS | |
| SCHEMBL1054548 | 0.85 | MAOA (0.73) | MAOACYP3A4PABPC1DNMT1CASP1 | |
| SCHEMBL29644349 | 0.85 | MAOA (0.73) | MAOACYP3A4PABPC1DNMT1CASP1 | |
| SCHEMBL23972209 | 0.85 | MAOA (0.73) | MAOACYP3A4PABPC1DNMT1CASP1 | |
| Fluoranthene SCHEMBL11227281 | 0.83 | MAOA (0.71) | MAOACYP3A4PABPC1DNMT1CASP1 | |
| SCHEMBL18573118 | 0.83 | MAOA (0.70) | MAOACYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178447-A | Polypyridine metal organic ruthenium complex of oxidized iso-aporphine alkaloid and synthetic method and application thereof | 广西师范大学 | 2023-05-30 | — | — | CN | disclosed |
| CN-116143842-A | Cyclometaliridium complex of oxidized iso-aporphine alkaloid and N-heterocyclic carbene, and synthetic method and application thereof | 广西师范大学 | 2023-05-23 | — | — | CN | disclosed |
| CN-116023417-A | N-heterocyclic carbene type cyclometalated ruthenium complex of oxidized iso-aporphine alkaloid, and synthetic method and application thereof | 广西师范大学 | 2023-04-28 | — | — | CN | disclosed |
| CN-110518450-B | Preparation method of light-induced condensing laser and light-induced condensing laser | 华南理工大学 | 2020-04-24 | — | — | CN | disclosed |
| US-8846920-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8846920-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| US-8846920-B2 | Metal complexes | MERCK PATENT GMBH (DE) | 2014-09-30 | — | — | US | disclosed |
| EP-1675929-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-06-22 | — | — | EP | disclosed |
| EP-1675929-B1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2011-06-22 | — | — | EP | disclosed |
| US-20100331506-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-20100331506-A1 | METAL COMPLEXES | MERCK PATENT GMBH (DE) | 2010-12-30 | — | — | US | disclosed |
| US-7820822-B2 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | MERCK PATENT GMBH (DE) | 2010-10-26 | — | — | US | disclosed |
| US-7820822-B2 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | MERCK PATENT GMBH (DE) | 2010-10-26 | — | — | US | disclosed |
| US-7820822-B2 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | MERCK PATENT GMBH (DE) | 2010-10-26 | — | — | US | disclosed |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | UDC IRELAND LIMITED (IE) | 2007-02-15 | — | — | US | disclosed |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | UDC IRELAND LIMITED (IE) | 2007-02-15 | — | — | US | disclosed |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | UDC IRELAND LIMITED (IE) | 2007-02-15 | — | — | US | disclosed |
| EP-1675929-A1 | METAL COMPLEXES | MERCK PATENT GmbH (DE) | 2006-07-05 | — | — | EP | disclosed |
| WO-2005033244-A1 | METAL COMPLEXES | COVION ORGANIC SEMICONDUCTORS GMBH (DE) | 2005-04-14 | — | — | WO | disclosed |
| US-4128650-A | Dibenzo[de, h]quinoline derivatives | RHONE-POULENC INDUSTRIES (FR) | 1978-12-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100331506-A1 | METAL COMPLEXES | SOD1, AP1M1, AP2M1 | MAOA 757/4885CYP3A4 581/4885PABPC1 2858/4885 |
| US-20070034863-A1 | fac-tris[7,7-difluoro-7H-dibenzo[de,h]quinoline-C2,N]iridium(III) (Ir1)A: 7,7-Difluorodibenzo[de,h]quinoline; use in organic electronic devices such as electroluminescent elements, and to their use in displays based thereon | NISCH, CISD1, AFF1 | MAOA 629/4885CYP3A4 696/4885PABPC1 4142/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.