SCHEMBL28075835

SCHEMBL28075835

O=C1c2ccccc2-c2nccc3cccc1c23.[Pt]

nearest known ligand 0.97

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MAOA P21397 2/20 0.97
CYP3A4 P08684 1/20 0.56
PABPC1 P11940 1/20 0.56
DNMT1 P26358 1/20 0.56
CASP1 P29466 1/20 0.56
CASP7 P55210 1/20 0.56
ALDH1A1 P00352 1/20 0.52
CTSL P07711 1/20 0.50
PTPRC P08575 1/20 0.50
CTSS P25774 1/20 0.50
PTPN13 Q12923 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1969983 0.98 MAOA (1.00) MAOACYP3A4PABPC1DNMT1CASP1
SCHEMBL30416588 0.97 MAOA (0.97) MAOACYP3A4PABPC1DNMT1CASP1
SCHEMBL29869412 0.84 MAOA (0.75) MAOACYP3A4PABPC1DNMT1CASP1
SCHEMBL25380689 0.84 MAOA (0.75) MAOACYP3A4PABPC1DNMT1CASP1
Sampangine SCHEMBL6230423 0.84 MAOA (0.74) MAOAALDH1A1CTSLPTPRCCTSS
SCHEMBL1054548 0.83 MAOA (0.73) MAOACYP3A4PABPC1DNMT1CASP1
SCHEMBL29644349 0.83 MAOA (0.73) MAOACYP3A4PABPC1DNMT1CASP1
SCHEMBL23972209 0.83 MAOA (0.73) MAOACYP3A4PABPC1DNMT1CASP1
Fluoranthene SCHEMBL11227281 0.82 MAOA (0.71) MAOACYP3A4PABPC1DNMT1CASP1
SCHEMBL18573118 0.82 MAOA (0.70) MAOACYP3A4ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105669763-A 9-amino oxidized isoaporphine-platinum (II) complex, synthetic method and application thereof 广西师范大学 2016-06-15 CN disclosed
CN-103450281-A 1-azabenzanthrone-platinum (II) complex as well as synthesis method and application thereof UNIV GUANGXI NORMAL 2013-12-18 CN disclosed
CN-103450281-A 1-azabenzanthrone-platinum (II) complex as well as synthesis method and application thereof UNIV GUANGXI NORMAL 2013-12-18 CN disclosed