SCHEMBL202695

SCHEMBL202695

C=C[Si](C)(N(C(C)=O)c1ccccc1)N(C(C)=O)c1ccccc1

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 6/20 0.39
ALDH1A1 P00352 4/20 0.39
MEN1 O00255 4/20 0.39
POLB P06746 1/20 0.39
MTNR1A P48039 1/20 0.38
MTNR1B P49286 1/20 0.38
NPSR1 Q6W5P4 1/20 0.36
TSHR P16473 3/20 0.36
L3MBTL1 Q9Y468 1/20 0.36
GLA P06280 1/20 0.35
AKT1 P31749 1/20 0.34
MAPT P10636 2/20 0.34
KDM4E B2RXH2 1/20 0.34
CRHBP P24387 1/20 0.34
CRHR2 Q13324 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.34
HPGD P15428 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2C19 P33261 1/20 0.33
APAF1 O14727 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9422275 0.84 KMT2A (0.40) KMT2AALDH1A1MEN1POLBMTNR1A
SCHEMBL508790 0.79 NPSR1 (0.43) KMT2AALDH1A1MEN1MTNR1AMTNR1B
SCHEMBL204288 0.79 NPSR1 (0.43) KMT2AALDH1A1MEN1MTNR1AMTNR1B
SCHEMBL8387202 0.79 NPSR1 (0.43) KMT2AALDH1A1MEN1MTNR1AMTNR1B
SCHEMBL9151256 0.74 MAPT (0.40) KMT2AALDH1A1MEN1MTNR1AMTNR1B
SCHEMBL15328662 0.72 ALDH1A1 (0.33) KMT2AALDH1A1MEN1NPSR1TSHR
SCHEMBL17830154 0.71 ALDH1A1 (0.36) KMT2AALDH1A1MEN1POLBMTNR1A
SCHEMBL26255290 0.71 KMT2A (0.37) KMT2AALDH1A1MEN1TSHRL3MBTL1
SCHEMBL273919 0.69 KMT2A (0.46) KMT2AALDH1A1MEN1POLBMTNR1A
SCHEMBL10508349 0.69 ALDH1A1 (0.41) KMT2AALDH1A1MEN1POLBMTNR1A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 97 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11814553-B2 Adhesive DOW SILICONES CORPORATION (US) 2023-11-14 US disclosed
CN-112823193-B Adhesive agent 美国陶氏有机硅公司 2023-09-15 CN disclosed
US-20210380856-A1 ADHESIVE DOW SILICONES CORPORATION 2021-12-09 US disclosed
EP-3874003-A1 ADHESIVE Dow Silicones Corporation (US) 2021-09-08 EP disclosed
EP-2875074-B1 ORGANOSILOXANE COMPOSITIONS DOW SILICONES CORP (US) 2019-09-18 EP disclosed
US-10308838-B2 Moisture curable compositions DOW SILICONES CORPORATION (US) 2019-06-04 US disclosed
EP-3118242-B1 BRANCHED ORGANOPOLYSILOXANES DOW SILICONES CORP (US) 2018-10-17 EP disclosed
EP-2155804-B1 A METHOD FOR MAKING PHENYLALKYLSILOXANES DOW SILICONES CORP (US) 2018-08-01 EP disclosed
US-20170174886-A1 Emulsions Of Branched Organopolysiloxanes DOW CORNING CORPORATION (US) 2017-06-22 US disclosed
US-9567503-B2 Organosiloxane compositions DOW CORNING CORPORATION (US) 2017-02-14 US disclosed
EP-0381321-A2 Method for forming a crosslinkable pressure-sensitive adhesive construction containing an aminoxysilicon compound and an amidosilicon compound DOW CORNING CORPORATION (US) 1990-08-08 EP disclosed
US-4889878-A SELF-LEVELING, MOISTURE CURABLE POLYSILOXANES; FILLERS, DIAMIDOVINYL SILANES, AMINOXYSILANES DOW CORNING CORPORATION (US) 1989-12-26 US disclosed
EP-0337478-A2 Concrete joint sealant having improved adhesion DOW CORNING CORPORATION (US) 1989-10-18 EP disclosed
EP-0337791-A2 Self leveling highway sealant DOW CORNING CORPORATION (US) 1989-10-18 EP disclosed
EP-0271296-A2 Syntactic sealants DOW CORNING CORPORATION (US) 1988-06-15 EP disclosed
EP-0216390-A2 Low consistency, one-part silicone elastomers DOW CORNING CORPORATION (US) 1987-04-01 EP disclosed
US-4614760-A POLYSILOXANES DOW CORNING CORPORATION (US) 1986-09-30 US disclosed
US-4555420-A DIFUNCTIONAL NITROGEN-CONTAINING SILANE CURING AGENTS; LOW MODULUS ENCAPPED POLYSILOXANES GENERAL ELECTRIC COMPANY (US) 1985-11-26 US disclosed
US-4020044-A REACTING WITH A VINYL DI-AMIDO SILANE DOW CORNING CORPORATION (US) 1977-04-26 US disclosed
US-3996184-A CONSTRUCTION MATERIALS DOW CORNING CORPORATION (US) 1976-12-07 US disclosed