Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | TSHR | P16473 | 3/20 | 0.41 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.40 |
| ▸ | MAPT | P10636 | 2/20 | 0.39 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.39 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 4/20 | 0.39 |
| ▸ | CRHBP | P24387 | 1/20 | 0.39 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.39 |
| ▸ | APAF1 | O14727 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CES2 | O00748 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL204288 | 0.87 | NPSR1 (0.43) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL508790 | 0.87 | NPSR1 (0.43) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL7938546 | 0.84 | NPSR1 (0.50) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL9151256 | 0.82 | MAPT (0.40) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL4433309 | 0.81 | NPSR1 (0.41) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL9623703 | 0.79 | NPSR1 (0.45) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL9468244 | 0.79 | KDM4E (0.49) | NPSR1ALDH1A1TSHRKMT2AKDM4E | |
| SCHEMBL202695 | 0.79 | KMT2A (0.39) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL22680922 | 0.78 | ALDH1A1 (0.46) | NPSR1ALDH1A1TSHRGLAKMT2A | |
| SCHEMBL9804612 | 0.78 | CES2 (0.38) | NPSR1ALDH1A1TSHRKMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5922449-A | HIGH PRESSURE LIQUID CHROMATOGRAPHY | DIAZEM CORPORATION (US) | 1999-07-13 | — | — | US | disclosed |
| US-5602077-A | CONTROLLING GROWTH OF UNDESIRED VEGETATION IN PLANTATION CROPS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| US-5567670-A | TETRAHYDROTRIAZINE-DIONE DERIVATIVES | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1996-10-22 | — | — | US | disclosed |
| EP-0623117-A1 | PYRIMIDIN COMPOUNDS USEFUL AS HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-11-09 | — | — | EP | disclosed |
| EP-0437911-B1 | Method for producing dual zone materials by catalyzed halosilylation | DOW CORNING (US) | 1993-11-18 | — | — | EP | disclosed |
| WO-1993014073-A1 | PYRIMIDIN COMPOUNDS USEFUL AS HERBICIDES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-07-22 | — | — | WO | disclosed |
| EP-0158500-B1 | POROUS MATERIALS HAVING A DUAL SURFACE | DOW CORNING CORPORATION (US) | 1992-07-15 | — | — | EP | disclosed |
| US-5110784-A | Dual surface porous material | DOW CORNING CORPORATION (US) | 1992-05-05 | — | — | US | disclosed |
| EP-0437911-A1 | Method for producing dual zone materials by catalyzed halosilylation | DOW CORNING CORPORATION (US) | 1991-07-24 | — | — | EP | disclosed |
| EP-0413464-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-20 | — | — | EP | disclosed |
| EP-0413465-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-02-20 | — | — | EP | disclosed |
| US-4981827-A | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-01 | — | — | US | disclosed |
| US-4950635-A | Method for producing dual zone materials by catalyzed halosilylation | DOW CORNING CORPORATION (US) | 1990-08-21 | — | — | US | disclosed |
| EP-0323082-A2 | Catalysts | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1989-07-05 | — | — | EP | disclosed |
| EP-0161058-B1 | DUAL SURFACE MATERIALS | DOW CORNING CORPORATION (US) | 1989-05-24 | — | — | EP | disclosed |
| US-4782040-A | Porous materials having a dual surface | DOW CORNING CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0165509-A1 | Process for the improvement of the solubility of certain organic compounds which are sparingly soluble in inert solvents by silylation with trialkylsilylcyanide | BAYER AG (DE) | 1985-12-27 | — | — | EP | disclosed |
| EP-0161058-A1 | Dual surface materials | DOW CORNING CORPORATION (US) | 1985-11-13 | — | — | EP | disclosed |
| EP-0158500-A2 | Porous materials having a dual surface | DOW CORNING CORPORATION (US) | 1985-10-16 | — | — | EP | disclosed |